Clinical and Experimental Pediatrics

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Original Article

Hematology

Effect of cyclic pamidronate administration on osteoporosis in children with β-thalassemia major: a single-center study

Mahmoud A. El-Hawy, Nagwan Y. Saleh

Clin Exp Pediatr. 2022;65(8):405-409. Published online June 7, 2022

Web of Science 1 Crossref 1

Question: What is the effect of cyclic pamidronate administration on osteoporosis in children with β-thalassemia major?
Finding: The dual-energy x-ray absorptiometry scan findings of children with β-thalassemia major and osteoporosis were improved after pamidronate administration.
Meaning: Cyclic pamidronate effectively treated osteoporosis in children with β-thalassemia major.

DOI: https://doi.org/10.3345/cep.2019.00535

Endocrinology

The effect of low-dose intravenous bisphosphonate treatment on osteoporosis in children with quadriplegic cerebral palsy

Soon Jeong Moon, Young Min An, Soon Ki Kim, Young Se Kwon, Ji Eun Lee

Clin Exp Pediatr. 2017;60(12):403-407. Published online December 22, 2017

Crossref 11

Purpose

Quadriplegic children with cerebral palsy are more susceptible to osteoporosis because of various risk factors that interfere with bone metabolism. Pamidronate is effective for pediatric osteoporosis, but there are no guidelines for optimal dosage or duration of treatment in quadriplegic children with osteoporosis. We aimed to evaluate the efficacy of low-dose pamidronate treatment in these patients.

Methods

Ten quadriplegic patients on antiepileptic...

DOI: https://doi.org/10.3345/kjp.2017.60.12.403

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