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Review Article
Once daily dosing of aminoglycoside in children
Seon Hee Shin
Clin Exp Pediatr. 2008;51(10):1038-1041.   Published online October 15, 2008
Aminoglycosides are frequently used antibiotics in children. The multiple daily dosing (MDD) in infants and children is twice or three times daily depending on age. Recent studies in adults have shown that once daily dosing (ODD) maximizes the bactericidal activity and might minimize the toxicity of antibiotics. So, I reviewed many studies about efficacy, toxicity and cost effectiveness of ODD...
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