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Review Article
Neurology
Rotavirus infection-associated central nervous system complications: clinicoradiological features and potential mechanisms
Kyung Yeon Lee
Clin Exp Pediatr. 2022;65(10):483-493.   Published online February 7, 2022
∙ Rotavirus infection-associated central nervous system (CNS) complications are fairly common in children.
∙ Common clinicoradiological features include benign convulsions with mild gastroenteritis, acute encephalopathies/encephalitis, cerebellitis, and neonatal rotavirus-associated leukoencephalopathy.
∙ Possible mechanisms for CNS complications include direct viral invasion into the brain via several potential routes such as the blood-brain barrier and vagus nerve, and entry of various brain-damaging mediators and activated immune cells into the brain.
Case Report
A childhood case of spinal tuberculosis misdiagnosed as muscular dystrophy
Doo Il Song, Su Ye Sohn, Yun Kyung Kim, So Hee Eun, Young Jun Rhie, Gi Young Jang, Chan Wook Woo, Byung Min Choi, Jung Hwa Lee, Bo Kyung Je
Clin Exp Pediatr. 2010;53(5):657-660.   Published online May 31, 2010

Tuberculosis is primarily a pulmonary disease, but extra-pulmonary manifestations are not uncommon, especially in children and adolescents. Ten percent of extra pulmonary tuberculosis localizes to the bones and joints, and 56% of such cases affect the spine. We treated a childhood case of spinal tuberculosis misdiagnosed as muscular dystrophy in a patient without specific constitutional symptoms. We report this case...

Original Article
Enterovirus 71-associated hand, foot and mouth diseases with neurologic symptoms, a university hospital experience in Korea, 2009
Hye Kyung Cho, Na Yong Lee, Hyunju Lee, Hae Soon Kim, Jeong Wan Seo, Young Mi Hong, Seung Joo Lee, Sun Wha Lee, Doo Sung Cheon, Ji Young Hong, Byung Hak Kang, Jong-Hyun Kim, Kyung-Hyo Kim
Clin Exp Pediatr. 2010;53(5):639-643.   Published online May 31, 2010
Purpose

Hand-foot-mouth disease (HFMD) is a common viral illness in children, which is usually mild and self-limiting. However, in recent epidemics of HFMD in Asia, enterovirus 71 (EV71) has been recognized as a causative agent with severe neurological symptoms with or without cardiopulmonary involvement. HFMD was epidemic in Korea in the spring of 2009. Severe cases with complications including death have...

Neurologic Complications after Hematopoietic Stem Cell Transplantation in Children
Moon Young Jeong, Young Kuk Cho, So Youn Kim, Young Ok Kim, Chan Jong Kim, Hoon Kook, Young Jong Woo, Tai Ju Hwang
Clin Exp Pediatr. 2004;47(9):978-985.   Published online September 15, 2004
Purpose : Neurologic complications(NC) after hematopoietic stem cell transplantation(HSCT) are important because of high mortality and severe sequelae. We analyzed the incidence, manifestation and risk factors of NC in 61 children undergoing HSCT. Methods : We retrospectively analyzed NC in 61 cases(42 male and 19 female, aged one to 16 years) given HSCT between 1996 and 2003 due to hematologic malignacies,...
A Clinical Study of Neurologic Abnormalities Associated with Rotavirus Gastroenteritis
Yoon-Duk Kang, Myung-Kul Yum, Jae-Won Oh, Chang-Ryul Kim, In-Joon Seol, Jung-Oak Kang
Clin Exp Pediatr. 2004;47(7):751-755.   Published online July 15, 2004
Purpose : Reports of neurologic abnormalities associated with acute diarrhea are increasing recently. It was reported that the incidence of the neurologic abnormalities related to gastroenteritis was higher in rotavirus gastroenteritis than in non-rotavirus gastroenteritis. We investigated the incidence, the manifestations and the prognosis of the neurologic abnormalities associated with rotavirus diarrhea and non-rotavirus diarrhea in Korean children. Methods : Six...
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