Clinical and Experimental Pediatrics

Original Article

Neonatology (Perinatology)

Incidence of neural tube defects in tertiary care university hospital in Bangladesh

Ismat Jahan, Arif Hossain, Shah Nizam Uddin Shaon, Sadeka Choudhury Moni, Mohammad Kamrul Hassan Shabuj, Sanjoy Kumer Dey, Mohammad Abdul Mannan, Mohammod Shahidullah

Clin Exp Pediatr. 2025;68(7):530-538. Published online April 1, 2025

Web of Science 1 Crossref 1

Question: What is the burden of neural tube defects (NTDs) in a tertiary care neonatal intensive care unit in Bangladesh?
Finding: The overall incidence of NTD was 6.4 (range, 4.59–11.2) per 1,000 live births, and the meningomyelocele complex was the most frequent location.
Meaning: The high incidence of NTD found in a leading tertiary care multidisciplinary referral hospital in Bangladesh may not reflect that of the wider population.

DOI: https://doi.org/10.3345/cep.2024.01578

A Study of Homocysteine Metabolism related Neural Tube Defect

Baeck Hee Lee

Clin Exp Pediatr. 1998;41(1):110-114. Published online January 15, 1998

Purpose : Methylenetetrahydrofolate reductase is an important enzyme in homocysteine metabolism. Since the identification of the gene locus and mutation of methylenetetrahydrofolate reductase, an increasing number of reports have suggested that elevated levels of homocysteine were associated with various kinds of arteriovascular disease and neural tube defect. Our research plans to investigate whether elevated levels of homocysteine are more common with neural tube defect and...

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Case Report

A Case of Meningomyelocele Combined with Arnold-Chiari Malformation.

Kyu Youp Kim, Hyeon Soo Park, Heung Jae Lee, Keun Soo Lee

Clin Exp Pediatr. 1981;24(12):1193-1196. Published online December 15, 1981

We had experienced a case of meningomyelocele combined with Arnold-Chiari malformation. This neonate had her birth weight of 2,960 gm after 41 weeks of gestation. At birth, he noticed the Apgar Score of 0, so he was resuscitated immediately. On physical examination, he noticed large head and fist sized mass on back. Inspite of intensive care, he was expired at 2...

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