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Case Report
A Case of Letterer-Siwe Disease.
Suh Hong Ha, Jeong Sil Han, Sung Won Kim, Kyung Tae Kim, Kil Hyun Kim, Chung Hee Chi
Clin Exp Pediatr. 1987;30(3):335-341.   Published online March 31, 1987
Letterer-Siwe disease is a variant of Histiocytosis X and characterized by onset in infancy, hepatosplenomegaly, lymphadenopathy, bleeding tendency, hypochromic anemia, fever, localized bone defect and fatal outcome. The diagnosis was confirmed by clinical symptoms, laboratory datas, histopathologic and radiologic findings. We experienced a case which was treated by single prednisolone method and resulted to good response. A brief review of literature was made.
A Case of Letter-Siew Disease.
Yoon Ho Kang, Suck Young Lee, Jin Sook Lee, Kwang Ho Kim, Soo Nam Lee
Clin Exp Pediatr. 1985;28(10):1032-1036.   Published online October 31, 1985
A case of Letterer-Siwe disease in a 6 month-old Korean male manifesting maculopapular skin rash, watery diarrhea, fever and bony skull defect as classical features of the disease was presented. The diagnosis was confirmed by clinical symptoms, histopathologic and radiologic findings. The authors report a fatal case which was treated in hospital with intensive antibiotics, corticosteroid and alkylating agent.
Three Cases of the Letterer-Siwe Disease.
M H Kim, E K Choi, M Y Chung, D H Keum
Clin Exp Pediatr. 1985;28(8):817-822.   Published online August 31, 1985
Letterer-Siwe disease was an established entity with the following fature: occurrence in infancy, hepatosplenomegaly, lymphadenopathy, bleeding diathesis, tumors of bone, generalized hyperplasia of nonlipid storing macrophages in many organs but prominently in skin, and rapidly fatal downhill course. The diognosis was confirmed by clinical symptoms, laboratory data, histopathologic and radiologic findings. During past 6 years, we experienced 3 cases of the disease...
A case of Letterer-Siwe disease.
H J Suh, E H Kang, K C Han, S K Moon
Clin Exp Pediatr. 1982;25(9):954-958.   Published online September 30, 1982
A case of Letterer-Siwe disease in a 2 year old boy manifesting such classic signs described by Siwe as, hepatosplenome^aly, swelling of lymph node, bleeding tendency, anemia, fever and bony skull defects is presented. The diagnosis was confirmed by clinical symptoms, laboratory data, histopathologic and radiologic fingings. The authors report a fatal case which was treated in this hospital with review of pertinent literatures.
A Case of Report of Letterer-Siwe Disease.
Nam Heon Kim, Jung Ho Lee, In Ho Kim, Churl Young Chung, Jong Eun Joo, Ill Hyang Ko
Clin Exp Pediatr. 1981;24(12):1213-1217.   Published online December 15, 1981
We experienced a cass of Letterer-Siwe disease in 2 month old infant. The patient was presented charateristic clinical findings such as hepatosplenomegaly, petechia, anemia, gene-ralized lymphadenopathy, and lung infiltration. The diagnosis was confirmed by lymphnode biopsy and bone marrow aspiration, which was compatible to Letterer-Siwe disease. A poor prognostic factor in Histiocytosis X is younger age (below 18 month), hepatospleno-megaly, anemia,...
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