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The hyperimmunoglobulin E syndrome is a primary immunodeficiency disorder characterized by
serious recurrent bacterial infections of the skin and respiratory system in early life, and markedly
elevated serum IgE level.
These recurrent infections are generally subcutaneous abscesses caused by Staphylococcus aureus.
Also, additional characteristrics of this syndrome include coarse facial appearance, chronic pruritic
dermatitis and eosinophilia.
The baisic immunologic defect mechanism in hyperimmunoglobulin E syndrome is... |
