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Original Article

Longitudinal analysis of gut microbiota dysbiosis and bacterial signatures predictive of postoperative enterocolitis in children with Hirschsprung disease

Sireekarn Chantakhow, Chanon Kunasol, Jiraporn Khorana, Kanokkan Tepmalai, Nipon Chattipakorn, Siriporn C Chattipakorn

Background: We aimed to investigate differences in gut microbiota between patients with Hirschsprung disease (HSCR) and healthy children; assess longitudinal changes in the microbiota of patients with HSCR from diagnosis through postoperative period; and identify microbial markers predictive of postoperative HSCR-associated enterocolitis (HAEC).
Purpose: To investigate alterations in the gut microbiota of patients with HSCR by assessing longitudinal microbiome changes after...

DOI: https://doi.org/10.3345/cep.2025.01886 [Accepted]

Review Article

Gastroenterology

High-resolution anorectal manometry in children

Yogesh Waikar

Clin Exp Pediatr. 2024;67(2):57-63. Published online June 14, 2023

Web of Science 2 Crossref 5

· Anorectal manometry is safe in children.
· Defecation Dyssynergia is one of the commonest cause of chronic constipation.
· Positive Rectoanal inhibiory reflex rules out Hirschsprung's Disease

DOI: https://doi.org/10.3345/cep.2022.01242

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