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Original Article
Neonatology (Perinatology)
Effectiveness of various nonpharmacological analgesic methods in newborns
Pancham Kumar, Rakesh Sharma, Sukhdev Rathour, Sunidhi Karol, Mohit Karol
Clin Exp Pediatr. 2020;63(1):25-29.   Published online August 16, 2019
Question: Can nonpharmacological methods be used for neonatal pain management.
Finding: Nonpharmacological methods like Sucrose, breastfeeding etc have shown to significantly reduce the pain caused by intramuscular hepatitis B vaccination.
Meaning: Nonpharmacological methods are the safe and cheap potential modalities of analgesia which can be used during mild to moderate pain in newborns.
A study of the current(2003-2005) prevalence of anti-HBs and immunologic memory of hepatitis B vaccine in children from the central area of Korea
Young Won An, Eun Hee Chung, Insoo Rheem
Clin Exp Pediatr. 2006;49(6):630-634.   Published online June 15, 2006
Purpose : This study was conducted to assess the current(2003-2005) prevalence of anti-HBs and immunologic memory for Hepatitis B vaccine in children from the central area of Korea. Methods : Subjects were chosen from children and adolescents who received tests for hepatitis B surface antigen(HBsAg) and anti-HBs at Dankook University Hospital from March 2003 to May 2005. Among these, antibodies to...
The Change of Anti-HBs Titer after Injection of HBIG and HBV in Newborn Delivered from HBsAg Carrier Mothers
Qoae Suk Roh, Jin Young Jung
Clin Exp Pediatr. 1997;40(8):1141-1148.   Published online August 15, 1997
Purpose : We studied prevention effects of vertical transmission of Hepatitis B with follow-up, through the change of Anti-HBs titers during 9 months after injection of Hepatitis B immunoglobulin(HBIG) and Hepatitis B vaccine(HBV) at birth in newborn delivered from Hepatitis antigen carrier mothers. Methods : This study was performed on newborn delivered from HBsAg carrier mothers at Hae Sung Hospital from Feb. 1995 to May...
The Change of Anti-HBs Titer after Hepatitis B Vaccination in Newborn According to Dosage and Time
Joon Young Lee, Yong Sik MIn, Chang hwi Kim, Sang Jhoo Lee
Clin Exp Pediatr. 1993;36(5):656-663.   Published online May 15, 1993
We studied anti-HBs titer, positive and effective rate in relation to dosages(5, 10) and time interval after third vaccination in 23 infants born to HBsAg negative mother. The babies were divided into two groups. In one group(n=12), 5 of Hepavax was administered intramusculary at 1 month, 2 months and 6 months age, in other group (n=11), 10 of Hepavax at...
The Effect of Hepatitis B Vaccination on Newborns of Hepatitis B Carrier Mothers.
Ho Taek Kom, Pyung Kil Kim, Chang Ho Hong, Chul Lee
Clin Exp Pediatr. 1987;30(11):1228-1235.   Published online November 30, 1987
The transmission of hepatitis B virus (HBV) from carrier mothers to their infants is a serious problem in many countries and the transmission rate is reported to be as high as 60%. The best preventive method of perinatal transmission is hepatitis B immune globulin (HBIG) which confers a passive immunity and HB vaccine which confers an active immunity. However, the exact dosage and the...
Immunogenecity of Low-Dose Administration of Hepatitis B Virus Vaccine in School Aged Group.
Young Mo Sohn, Pyung Kin Kim, Kyung Soon Song
Clin Exp Pediatr. 1987;30(11):1221-1227.   Published online November 30, 1987
For evaluation of immunogenecity of low-dose of hepatitis vaccine-prepared by Korea Green Cross Corporation 74 school aged children were given routine schedule (0, 1, 6 months). A dose of 5 microgram was administered intramuscullary in the cases of age under 10 yrs of age and 10 microgram was administered in the cases over 11 yrs of age. An adequate follow-up observation of antibody titer...
The relationship between Dose of Hepatitis B Vaccine and Seroconversion Rate in Infants.
Jung Hye Choi, Ki Sup Chung, Dong Gwan Han
Clin Exp Pediatr. 1986;29(10):1080-1086.   Published online October 31, 1986
After the discovery of Australia antigen by Blumberg et al in 1965, subsequent studies revealed that Australia antigen is identical with surface antigen of hepatitis B virus. The infants born to HBsAg positive mother can be protected from perinatal hepatitis B virus infection with hepatitis B vaccine and hepatitis B immunoglobulin. If the dose of vaccine can be reduced from...
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