Clinical and Experimental Pediatrics

Search

Page Path

HOME
Search

Original Article

A Study of the Bystander Effect and Its Enhancement in HSV-TK Gene Therapy Using a Murine Neuroblastoma Model

Hyun Sang Cho, Moon Kyu Kim, Chong Young Park

Clin Exp Pediatr. 2002;45(3):354-361. Published online March 15, 2002

Purpose : Selective introduction of genes conferring chemosensitivity into proliferating tumor cells may be used to treat cancer. We first investigated the bystander effect of retrovirus-mediated gene transfer of herpes simplex virus thymidine kinase(HSV-TK) gene to murine neuroblstoma cell line(neuro-2a) in vitro and in vivo. Second, we examined the mechanism and its enhancement of the bystander effect in murine neuroblastoma. Methods...

MOST CITED ACCEPTED ARTICLES

Cited By 56	Prevalence of anxiety, depression, and stress among parents of neonates admitted to neonatal intensive care unit: a systematic review and meta-analysis
Cited By 36	Community-acquired pneumonia in children: updated perspectives on its etiology, diagnosis, and treatment
Cited By 36	Metabolic complications of obesity in children and adolescents
Cited By 33	Microplastic and human health with focus on pediatric well-being: a comprehensive review and call for future studies
Cited By 33	Neonatal family-centered care: evidence and practice models

+more

Virtual reality for managing pain and fear and anxiety during pediatric needle procedures: an umbrella review

Patient-independent automated pediatric seizure monitoring based on expert-labeled electrographic ictal data as core reference knowledge

Peters anomaly: a rare etiology of corneal clouding in the newborn

Prognosis of pediatric hepatic Wilson disease with ATP7B loss of function variants

Efficacy and safety of home-based fiberoptic blanket versus hospital-based light-emitting diode phototherapy for neonatal jaundice: a retrospective cohort study from Thailand

+more

ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES

FOR CONTRIBUTORS

ABOUT

Editorial Office: Korean Pediatric Society
#1606 Seocho World Officetel, 19 Seoun-ro, Seocho-ku, Seoul 06732, Korea
Tel: +82-2-3473-7306 Fax: +82-2-3473-7307 E-mail: office@e-cep.org

Clinical and Experimental Pediatrics is an open access journal. All articles are distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/)