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Original Article
Genetics and Metabolism
Neonatal indirect hyperbilirubinemia and glucose-6-phosphate dehydrogenase deficiency
Hasan M. Isa, Masooma S. Mohamed, Afaf M. Mohamed, Adel Abdulla, Fuad Abdulla
Clin Exp Pediatr. 2017;60(4):106-111.   Published online April 25, 2017
Purpose

This study aimed to determine the prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency among infants with neonatal indirect hyperbilirubinemia (NIH); compare G6PD-deficient and G6PD-normal patients regarding hyperbilirubinemia and need for exchange transfusions (ET); and assess risk factors for ET and kernicterus.

Methods

This is a case-control retrospective study. Medical records of NIH patients admitted to the Pediatric Department, Salmaniya Medical Complex, Bahrain, between...

Case Report
Successful treatment by exchange transfusion of a young infant with sodium nitroprusside poisoning
Jong Geun Baek, Hoar Lim Jeong, Ji Sook Park, Ji Hyun Seo, Eun Sil Park, Jae Young Lim, Chan Hoo Park, Hyang Ok Woo, Hee Shang Youn, Jung Sook Yeom
Clin Exp Pediatr. 2010;53(8):805-808.   Published online August 31, 2010

Although sodium nitroprusside (SNP) is often used in pediatric intensive care units, cyanide toxicity can occur after SNP treatment. To treat SNP-induced cyanide poisoning, antidotes such as amyl nitrite, sodium nitrite, sodium thiosulfate, and hydroxycobalamin should be administered immediately after diagnosis. Here, we report the first case of a very young infant whose SNP-induced cyanide poisoning was successfully treated by...

Original Article
Exchange Transfusion Using Percutaneous Femoral Vein Catheterization in Neonates: Comparison with Umbilical Vein Catheterization
Song-Ja Kim, Hyang-Ok Woo, Seung-Hwan Kim, Mi-Ryeong Kim, Sun-Kyeong Sin, Hee-Shang Youn
Clin Exp Pediatr. 1994;37(2):180-184.   Published online February 15, 1994
Traditionally umbilical vein has been used for exchange transfusion in neonates. This method is relatively safe and effective but with a few complications. So via percutaneous femoral vein catheters we tried exchange transfusion in 30 patients with neonatal hyperbilirubinemia admitted to GNUH from September 1990 to August 1992. Femoral vein catheterization succeeded in 2~3 trials. In all cases high bilirubin level...
A Clinical Study on Neonatal Exchange Transfusion
Eun Ju Park, Eun Wui Kim, Yang Sook Choi, Son Sang Seo
Clin Exp Pediatr. 1993;36(4):469-477.   Published online April 15, 1993
Clinical observation was perfumed on 81 cases who were received exchange transfusion at Ilsin Christian Hospital from January, 1986 to December, 1990. The results obtained were as follows: 1) Among 6,388 cases of neonatal jaundice, the exchange transfusion was performed on 81 cases(1.27%) 2) There was no sex predominance (male 40, female 41). The birth weight of 75 cases(92.6%) ranged from 2,500 gm...
The role of exchange transfusion as a therapy for neonatal DIC.
Jung Tak Kim, Kook In Park, Ran Namgung, Dong Gwan Han, Kir Young Kim
Clin Exp Pediatr. 1991;34(1):31-40.   Published online January 31, 1991
A clinical study on the effects of exchange transfusion on disseminated intravascular coagulation was conducted on 32 patients with DIC who were admitted to the pediatric department of YUMC from January 1984 to June 1989. We diagnosed DIC when symptoms were compatible to the diagnosis and there were more than 3 abnormal laboratory findings out of the following 5, which were platelet count, PT,...
A Clinical study on the Neonatal Exchange Transfusion.
S Y Song, W H Kwon, C H Han, H L Jeong, S Y Kim, Y D Kwon
Clin Exp Pediatr. 1990;33(2):162-169.   Published online February 28, 1990
A clinical observation was performed on patients with neonatal hyperbilirubinemia who were treated by exchange transfusion, and following results were obtained. Exchange transfusion was performed in 31 cases (8% of 383 csases admitted due to neonatal hyperbilirubinemia during the observation period). There was no sex predominance (male 16, female 15). Most common type of delivery was normal varginal delivery (22 cases, 71%). Birth weight of 17...
Acid-Base and Electrolyte Change Before and After Exchange Transfusion with ACD-B Blood in Hyperbilirubinemia of Newborn.
Ki Hong Park, Chong Woo Bae, Yong Mook Choi, Chang Ill Ahn, Jung Kook Lee
Clin Exp Pediatr. 1989;32(3):311-320.   Published online March 31, 1989
Exchange transfusion is being used widely to correct anemia and control existing hyperbilirubinemia for the prevention of kernicterus in newborn. But the blood used for exchange transfusion is stored blood containing anticoagulants and other substances. So many metabolic changes can be developed after exchange transfusion. This study was undertaken to evaluate the acid-base and electrolyte change after exchange transfusion using the ACD-B blood. In...
Clinical Studies on Neonatal Jaundice and Exchange Transfusion.
Byoung Hun Kim, Soo Yup Lee, Jeh Hoon Shin, Kyu Hwan Lee, Soo Jee Moon, Chong Moo Park
Clin Exp Pediatr. 1986;29(5):535-542.   Published online May 31, 1986
Jaundice occurs rather frequently in neonatal period, and yet the irreversible complication, kernicterus, may occur in severe cases with pathologic jaundice, from which the patients are at high risk for mental retardation, cerebral palsy, and even death. To prevent this complication, aggressive measures have been used for the neonatal janudice, such as phototherapy and exchange transfusion. Exchange transfusion has been...
A Study of 60 Cases of Exchange Transfusion.
Si Bok Jo, Im Ju Kang, Jae Keun Yoon, Hae Jin Suh
Clin Exp Pediatr. 1984;27(11):1055-1062.   Published online November 30, 1984
Clinical study was made of 60 cases who were received blood exchange transfusion at Taegu Fatima Hospital from January, 1978 to December, 1980 with the following results. 1) Among 1,387 cases of neonatal hyperbilirubinemia, the exchange transfusion was performed on 60 ases(4.3%). 2) The most predominant delivery type was normal vertex delivery at local clinics. 3) The most common cause of performed exchange transfusion was unknown...
The Response of Leukocytes in the Peripheral Blood Following Exchange Transfusion in the Newborn.
Young Mo Sohn, Yu Young Chang, Young Ho Kim, Kir Young Kim
Clin Exp Pediatr. 1983;26(11):1049-1054.   Published online November 30, 1983
We have studied the hemoglobin level and. leukocyte count of 23 fullterm and 1 premature jaundiced babies soon after exchange transfusion and daily thereafter until 7 days. The resixlts are: 1) One exchange transfusion was enough in 16 patients but 8 were required more than 2times of exchange transfusion. The maximum is 6 times. 2) The postnatal age was...
Clinical and Follow up Study of 52 cases of Blood Exchange Transfusion for Neonatal Hyperbilirubinemia.
Hong In Eum, Jae Gae Rheu, Sang Cheol Lee, Jung Hee Lee
Clin Exp Pediatr. 1983;26(10):996-1003.   Published online October 31, 1983
The study was made of 52 cases of neonatal hyperbilirubinemia receiving blood exchange transfusion at St. Benedict Hospital from January 1977 to June 1981 with the following results; 1) 34.6% of total exchanged patients were born at St. Benedict hospital. Remains were born at outside. 2) 27 patients(51.9%) returned for follow up, 21 patients(40.4%) not returned for follow up 4 patients (7.7%) had died. 3) The...
The Study on 182 Cases of Exchange Transfusion.
Gie Hwa Yoon, Ock Seung Jeong, So Won Ahn, Yung Seok Jeon
Clin Exp Pediatr. 1982;25(12):1243-1251.   Published online December 31, 1982
Clinical and statistical observations were performed on 182 cases who were received blood exchange transfusions at II Sin Women’s Hospital from January, 1978. to December, 1980. The results are as follows: 1. Among 1534 case of neonatal jaundice, the exchange transfusion was performed on 182 cases (8.4%). 2. The most predominant etiologies of exchange transfusion were ABO incompatibility (37.4 %) and prematurity(20.9%). 3. The total incidence of repeated exchange transfusion...
Case Report
Hyperviscosity Syndrome in Newborn.
Yong Soon Kim, Sook Hee Lee, Ja Hoon Koo, Doo Hong Ahn
Clin Exp Pediatr. 1982;25(6):622-627.   Published online June 30, 1982
We experienced Hyperviscosity syndrome in 5 newborn infants during 6 months period from August 1980 to January 1981. Diagnosis was made on the basis of characteristic clinical symp-toms along with polythemia. The following results were obtained. Sex in 5 affected infants showed male in 2 and female in 3. And gestational age showed preterm in 3 and full term in...
Original Article
A Follow-up Study of Newborns who had Exchange Blood Transfusion for Hyperbilirubinemia.
Young Soo Yoon, Seung Joon Park, Ki Bok Kim
Clin Exp Pediatr. 1981;24(9):826-836.   Published online September 15, 1981
A follow up study was made of 59 cases of neonatal hyperbilirubinemia receving blood exchange transfusion at Kwangju Christian Hospital from early 1976 to early 1979, with the following results. 1. 42patients(71.2%) returned for followup: 12 patients(20.3%) did not return; and 5 patients(8.5%) had died. 2. Of those returning, developmental status was studied by D.D.S.T. 38 patients(90.5%) had normal development...
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