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Review Article
Neonatology (Perinatology)
Bronchopulmonary dysplasia: how can we improve its outcomes?
Tae-Jung Sung
Clin Exp Pediatr. 2019;62(10):367-373.   Published online May 17, 2019
Bronchopulmonary dysplasia (BPD) is a chronic lung disease of preterm infants with multiple factors affected from prenatal to postnatal periods. Despite significant advances in neonatal care over almost 50 years, BPD rates have not decreased; in fact, they may have even increased. Since more preterm infants, even at periviable gestational age, survive today, different stages of lung development affect the...
Original Article
Prevention of Chronic Lung Disease with Early Dexamethasone Treatment in less than 32 Weeks Premature : Randomized Controlled Study
So Yun Shim, Su Jin Cho, Eun Ae Park
Clin Exp Pediatr. 2004;47(5):521-526.   Published online May 15, 2004
Purpose : The optimal timing and the consequences of dexamethasone therapy in chronic lung disease remain unknown. The purpose of this study was to determine whether early dexamethasone therapy would reduce the incidence of chronic lung disease and to determine the adverse effects and complications of prematurity associated with such therapy. Methods : Twenty neonates with hyaline membrane disease(dexamethasone n=10, placebo...
The Effect of Post-natal Weight Changes on the Development of Bronchopulmonary Dysplasia in Infants with Respiratory Distress Syndrome
Hye One Jhon, Young Min Kim, Hee Joo Hong, Chong Woo Bae
Clin Exp Pediatr. 2004;47(3):269-274.   Published online March 15, 2004
Purpose : The subjects were compared and measured for differences in the aspects of weight changes between the groups that developed bronchopulmonary dysplasia(BPD) after treatment and those that did not, to analyze the relations between the patterns of early weight change after birth and the development of BPD. Methods : Retrospective analysis of medical records were performed for birth weight and...
The Effect of Histologic Chorioamnionitis on the Development of Respiratory Distress Syndrome and Chronic Lung Disease in Preterm Infants
Heui seung Jo, Beyong Il Kim, Chang Won Choi, Jun Dong Park, Chong Jai Kim, Jung-Hwan Choi
Clin Exp Pediatr. 2004;47(2):150-156.   Published online February 15, 2004

Purpose: Histologic chorioamnionitis may play a role in the development of respiratory distress syndrome(RDS) and chronic lung disease(CLD) independently or through its association with preterm birth. We investigated the relationship between histologic chorioamnionitis and clinical complications including, RDS and CLD, of preterm infants. Methods: Clinical data were collected retrospectively from 478 preterm infants(gestational period≤34 weeks) who were admitted to the neonatal...
Classification and Risk Factors for Chronic Lung Disease(CLD) of Prematurity : Classical CLD Versus Atypical CLD
Chang Won Choi, Beyong Il Kim, Heui Seung Jo, Jun Dong Park, Chong Jae Kim, Bo Hyun Yoon, Jung-Hwan Choi
Clin Exp Pediatr. 2001;44(11):1222-1232.   Published online November 15, 2001
Purpose : We tried to classify the different type of CLD and assess the risk factors for classical CLD and atypical CLD. Methods : Retrospective cohort analysis was done in 120 preterm infants with birth weights less than 1,500 g who were admitted to NICU in Seoul National University Children's Hospital between Jan. 1993 and Dec. 1998 and survived more...
Growth and Neurodevelopmental Outcome at 15 Months of Corrected Age in Very Low Birth Weight Infants with Chronic Lung Disease
Seon Young Kim, Chang Yee Cho, Young Youn Choi
Clin Exp Pediatr. 2001;44(10):1112-1118.   Published online October 15, 2001
Purpose : This study was performed to compare the growth and neurodevelopmental outcome at 15 months of corrected age in very-low-birth weight infants between chronic lung disease(CLD) group and the control group. Methods : Very-low-birth-weight infants who were admitted and survived in the NICU(neonatal intensive care units) of Chonnam Univeristy Hospital from Jan. 1997 to Jan. 2000 were divided into...
A Study on the Effect of the Combined Use of Gentle Ventilation and High-Frequency Ventilation on the Incidence of Chronic Lung Disease
Ji Yeon Baek, Jae Han Kim, Kyung Ae Park, Suk Ho Kang, Man Hoe Hur, Sang Geel Lee
Clin Exp Pediatr. 2000;43(12):1544-1551.   Published online December 15, 2000
Purpose : This study was conducted to determine the correlation between the incidence of chronic lung disease and the combined use of gentle ventilation and high-frequency ventilation. Methods : The subject group consisted of 63 very low birthweight infants of less than 1500gm who were born and survived through ventilator treatment in the Fatima neonatal intensive care unit for four...
Genital Mycoplasmasin the Newborn Infants: Colonization, Prevalence and Clinical Significance
Yun Sil Chang, Sung Gwon Kim, Beyong Il Kim, Won Soon Park, Bo Hyun Yoon, Eui Chong Kim, Jung-Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1996;39(8):1084-1094.   Published online August 15, 1996
Purpose : The genital mycoplasmas: Ureaplasma urealyticum and Mycoplasma hominis have recently assumed an increasing importance as neonatal pathogens especially in preterm infants. The aim of the present study was to determine the prevalence of infections with these organisms in newborn infants who were admitted in Neonatal Intensive Care Unit(NICU) and who were suspected having infection in newborn nursery Methods : Sixty four inborns who...
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