Clinical and Experimental Pediatrics

Original Article

Efficacy and safety of carbon dioxide versus room-air insufflation in pediatric colonoscopy: a randomized controlled trial

Ajay Aravind, Ujjal Poddar, Anshu Srivastava, Moinak Sen Sarma

Background: Adequately powered studies in children are scarce and there are reports on the risk of carbon dioxide (CO2) retention after colonoscopy.
Purpose: This study investigated the efficacy and safety of CO2 insufflation in children undergoing colonoscopy. Methods: This prospective randomized clinical trial was conducted at a tertiary care hospital between March 2023 and July 2024. We recruited 200 consecutive children...

DOI: https://doi.org/10.3345/cep.2024.02012 [Accepted]

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Neonatology (Perinatology)

Effect of high-frequency oscillatory ventilation with intermittent sigh breaths on carbon dioxide levels in neonates

Kulthida Baingam, Anucha Thatrimontrichai, Manapat Praditaukrit, Gunlawadee Maneenil, Supaporn Dissaneevate

Clin Exp Pediatr. 2025;68(2):178-184. Published online November 13, 2024

Question: Can sigh breaths (Sighs) application during high-frequency oscillatory ventilation (HFOV) decrease partial pressure of carbon dioxide (PaCO₂) levels?
Finding: The mean PaCO₂ level after Sighs during HFOV was significantly decreased compared to that after HFOV alone (mean difference, -3.6 mmHg).
Meaning: HFOV plus Sighs functionality can reduce PaCO₂ levels. However, further studies are required to conclusively determine the effects of Sighs.

DOI: https://doi.org/10.3345/cep.2024.01011

Transcutaneous Oxygen and Carbon Dioxide Monitoring in Critically Ill Neonates.

Du Young Choi, Yong Kweon Kim, Yeon Kyun Oh

Clin Exp Pediatr. 1990;33(9):1202-1208. Published online September 30, 1990

We studied the correlation of 85 paired arterial, transcutaneous P02 and 50 paired arterial, trans- cutaneous PCO2, which were obtained from 9 sick preterm infants within first week of their life, who were bom at the Wonkwang University Hospital from March. 1, 1988 to Feb. 28, 1989. And we also analysed the affect of the pH, body temperature, hematocrit and birth weight to...

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