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Review Article

Oxidative stress and the antioxidant enzyme system in the developing brain

So-Yeon Shim, Han-Suk Kim

Clin Exp Pediatr. 2013;56(3):107-111. Published online March 18, 2013

Preterm infants are vulnerable to the oxidative stress due to the production of large amounts of free radicals, antioxidant system insufficiency, and immature oligodendroglial cells. Reactive oxygen species (ROS) play a pivotal role in the development of periventricular leukomalacia. The three most common ROS are superoxide (O2^•-), hydroxyl radical (OH^•), and hydrogen peroxide (H₂O₂). Under normal physiological conditions, a balance...

DOI: https://doi.org/10.3345/kjp.2013.56.3.107

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