Clinical and Experimental Pediatrics

Original Article

General Pediatrics

Effect of 2–6 weeks of systemic steroids on bone mineral density in children

Athira Kuniyil, Somdipa Pal, Namrita Sachdev, Tribhuvan Pal Yadav

Clin Exp Pediatr. 2022;65(5):254-261. Published online November 18, 2021

Question: Does steroid use for 2–6 weeks in children affect bone mineral content (BMC) or density (BMD)?
Finding: Steroid use for 2–6 weeks significantly decreased BMC and BMD of the whole body, total body less the head, lumbar spine, and distal radius. A significant negative correlation was observed among BMD, duration, and cumulative dose.
Meaning: Steroid use for 2–6 weeks in children negatively affected BMC and BMD.

DOI: https://doi.org/10.3345/cep.2021.00045

Effects of Growth Hormone Treatment on Alterations of Growth and Bone Metabolism in Rats Induced by Dexamethasone Administration

Woo Yeong Chung, Jeong Nyu Lee, Hye Kyoung Yoon

Clin Exp Pediatr. 1999;42(7):991-1002. Published online July 15, 1999

Purpose : The aim of this study was to investigate the alterations of growth and bone metabolism in SDR induced by dexa administration and to evaluate the effects of GH treatment in dexamethasone(dexa) induced growth and bone metabolism in SDR. Methods : Forty-five female Sprague-Dawley rats(weight 150-170gm) were divided in 3 groups: Group 1(n=15) received normal saline as control, Group 2(n=15)...

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Bone Mineral Metabolism and Rickets Compared between Fortified Human Milk and Preterm Formula Feeding in Prematurity

Hong Sun Ju, Eun Young Jeong, Seong Sook Jeon, Son Sang Seo

Clin Exp Pediatr. 1998;41(11):1476-1483. Published online November 15, 1998

Purpose : To compare the effect of breast milk containing fortifier with preterm formula on bone mineral metabolism in premature infants, we evaluated the state of bone mineralization, biochemical alteration and the frequency of rickets during the first five months of life. Methods : Fourteen fortified breast milk-fed infants and eleven preterm formula-fed infants who were born at Il-Sin...

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Cited By 22	Retinopathy of prematurity: a review of epidemiology and current treatment strategies
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Cited By 13	Etiological and pathophysiological enigmas of severe coronavirus disease 2019, multisystem inflammatory syndrome in children, and Kawasaki disease

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