Clinical and Experimental Pediatrics

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Original Article - Clinical trial

Effect of vitamin C supplement in treatment of childhood pneumonia requiring hospitalization: A randomized controlled trial

Chutima Phuaksaman, Katechan Jampachaisri, Klaita Srisingh

Background: The role of vitamin C in children with community-acquired pneumonia (CAP) in children is controversial; moreover, a standard dose is lacking.
Purpose: This study aimed to evaluate the ability of vitamin C to reduce symptom severity and length of hospital stay among children with CAP as well as determine its optimal dose. Methods: This randomized controlled clinical trial...

DOI: https://doi.org/10.3345/cep.2024.01970 [Accepted]

Review Article

Oxidative stress and the antioxidant enzyme system in the developing brain

So-Yeon Shim, Han-Suk Kim

Clin Exp Pediatr. 2013;56(3):107-111. Published online March 18, 2013

Crossref 63

Preterm infants are vulnerable to the oxidative stress due to the production of large amounts of free radicals, antioxidant system insufficiency, and immature oligodendroglial cells. Reactive oxygen species (ROS) play a pivotal role in the development of periventricular leukomalacia. The three most common ROS are superoxide (O2^•-), hydroxyl radical (OH^•), and hydrogen peroxide (H₂O₂). Under normal physiological conditions, a balance...

DOI: https://doi.org/10.3345/kjp.2013.56.3.107

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Clinical and Experimental Pediatrics is an open access journal. All articles are distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/)