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Review Article

Efficacy and effectiveness of extended-valency pneumococcal conjugate vaccines

Hyunju Lee, Eun Hwa Choi, Hoan Jong Lee

Clin Exp Pediatr. 2014;57(2):55-66. Published online February 24, 2014

The 7-valent pneumococcal protein conjugate vaccine (PCV7) has been shown to be highly efficacious against invasive pneumococcal diseases and effective against pneumonia and in reducing otitis media. The introduction of PCV7 has resulted in major changes in the epidemiology of pneumococcal diseases. However, pneumococcal vaccines induce serotype-specific immunity, and a relative increase in non-vaccine serotypes has been reported following the...

DOI: https://doi.org/10.3345/kjp.2014.57.2.55

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