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Original Article
Health Assessment of Handicapped Children in an Asylum
Eun Ju Lee, Eun Sil Lee, Han Ku Moon, Yong Hoon Park, Son Moon Shin
Clin Exp Pediatr. 2000;43(9):1263-1268.   Published online September 15, 2000
Purpose : To evaluate the health status of institutionalized handicapped children, a general health assessment was done in an asylum in Taegu in May 1998. Methods : Body measurements, including height, weight, head circumference, skin fold thickness and mid-arm circumference, were done with physical examination on 53 children. Blood tests and chest radiography were done, and fat impedance was measured....
Hepatitis B Virus Pre-S Gene Mutations in Children with Chronic Hepatitis B Infection
Jae Young Kim, Woo Yeong Chung, Chul Ho Kim
Clin Exp Pediatr. 2000;43(9):1232-1240.   Published online September 15, 2000
Purpose : The envelope of HBV consists of three polypeptides which are encoded in pre-S/S open reading frame. Three translation initiation sites are present within this pre-S/S open reading frame, i.e. pre-S1, pre-S2, and S, allowing the expression of large, middle and small HBs proteins. The pre-S1 is thought to carry the receptor binding site for viral entry into hepatocyte...
A Study of Clinical Features of Acute Tumor Lysis Syndrome in Children
Ick-Jin Song, Young-Tak Lim
Clin Exp Pediatr. 2000;43(7):952-958.   Published online July 15, 2000
Purpose : Tumor lysis syndrome is characterized by hyperuricemia, hyperphosphatemia, hyperkalemia and hypocalcemia due to destruction of tumor cells. The purpose of this study is to estimate in children the incidence, onset time, differences in outcomes between hemodialysis and conservative therapy, and predictive factor of tumor lysis syndrome before treatment with chemotherapy. Methods : Subjects were 108 children who had received...
Mutations in Hepatitis B Virus Precore and Core Promotor in Children with Chronic Hepatitis B Infection - Comparison Between Vertical and Non-vertical Transmission -
Jin Kuk Kim, Yeong Hong Park, Woo Yeong Chung, Chul Ho Kim
Clin Exp Pediatr. 2000;43(6):779-791.   Published online June 15, 2000
Purpose : The aims of this study were to investigate the frequencies and role of hepatitis B virus(HBV) precore and core promotor mutations in children with chronic hepatitis B infection. Methods : Sera from 46 children with chronic hepatitis B infection were analyzed by direct sequencing of polymerase chain reaction product of HBV DNA. In this study, the patients were divided...
Typing of Epstein-Barr Virus in Healthy Korean Children and Adults
Jin Han Kang, Jae Kyun Hur, Joeng Hyun Kim, Ahn Hee Lee
Clin Exp Pediatr. 2000;43(5):644-649.   Published online May 15, 2000
Purpose : Recently, the list of Epsterin-Barr Virus(EBV)-associated diseases has been growing. It is now known that there are two types(type 1 & 2) of EBV, but it has yet to be fully investigated as to whether type B EBV differs in any way from type A virus in terms of geographical distribution or disease association. We performed this study...
Clinical Study of Recurrent Parotitis in Children
Sam-Hwa Yim, Kye-Nam Yoon, Kyung-Yil Lee, Sang-Won Cha, Dong-Jun Lee, Ji-Whan Han, Jin-Han Kang, Kyung-Tai Whang
Clin Exp Pediatr. 2000;43(5):619-624.   Published online May 15, 2000
Purpose : Recurrent parotitis is defined as a recurrent parotid inflammation, generally associated with sialectasis of the parotid gland. It can often be misdiagnosed as recurrent mumps. We studied the clinical and laboratory features of recurrent parotitis. Methods : Outpatient clinical records of 23 cases were analyzed retrospectively between April 1993 and March 1999. Follow-up after the last outpatient clinic...
Analysis of Risk Factors of Readmission to Hospital for Pediatric Asthma
Kyung Lim Yoon, Young Ho Rah, Chong-Woo Bae, Sa Jun Chung
Clin Exp Pediatr. 2000;43(4):556-560.   Published online April 15, 2000
Purpose : The admission rates for pediatric asthma are increasing annually and are partially responsible for the increased rates of readmission. Selections of children with a high-risk of readmission and aggressive treatments of them may improve treatment outcome and cost- effectiveness. The purpose of this study is to evaluate the risk factors affecting readmission in cases of bronchial asthma in...
Effect of Liver Transplantation in Children with Fulminant Hepatitis
Young Mee Seo, Bo Hwa Choi, Kyung Mo Kim, Kwang Min Park, Young Joo Lee, Sung Gyu Lee
Clin Exp Pediatr. 2000;43(4):535-542.   Published online April 15, 2000
Purpose : Liver transplantation(LT) is regarded as an important management option for fulminant hepatitis(FH), which is associated with considerable mortality under conservative management. The aim of this study was to evaluate the outcome of children with FH according to management. Methods : We reviewed medical records of patients presented with FH from January 1994 until April 1999. The children were...
Case Report
A Case of Bilateral Tubo-Ovarian Abscesses in a One-and-Half Year-Old Girl
Mun Hee Kim, Young Kyoo Shin, Baik Lin Eun, Sun Han Kim, Hai Joong Kim, Sang Hoon Cha, Young-Sik Kim
Clin Exp Pediatr. 2000;43(3):432-437.   Published online March 15, 2000
Tubo-ovarian abscess is an end-stage disease of acute pelvic inflammatory disease(PID). Since most cases of PID are caused by sexually transmitted microorganisms, this is very rare in children. Here, we report an 1¨o-year-old girl with bilateral tubo-ovarian abscesses. She was admitted to our department with chief complaints of fever, vomiting and diarrhea. Abdominal ultrasonography and CT scanning of the patient...
Original Article
Treatment of Tachycardia by Radiofrequency Catheter Ablation in Children and Adolescents
Sung Jae Lee, Mi Jin Jung, Sung Ho Kim, Walter C. Schueller, Gil Hyun Kim, Hak Soo Lee
Clin Exp Pediatr. 2000;43(2):210-215.   Published online February 15, 2000
Purpose : RFCA has been proven to be an effective and safe tool for treating different kinds of tachycardia in adults. This study was designed to analyze the efficacy of this method in children and adolescents. Methods : Seventy-eight patients referred to Gachon Medical School, Gil Hospital for ablation of supraventricular(SVT) and ventricular tachycardia(VT) between January 1997 and February 1999 were...
A Clinical Study of Adenoviral Respiratory Infection in Children
Hong Keun Kim, Se Chang Ham, Seung Yeon Nam, Young Jae Koh, Kang Mo Ahn, Sang Il Lee
Clin Exp Pediatr. 2000;43(2):195-202.   Published online February 15, 2000
Purpose : Adenoviral respiratory infection can develop a life threatening condition similar to severe bacterial pneumonia. Despite adequate intensive care, this infection progresses to acute respiratory distress syndrome and causes permanent lung damage in some patients. In this study, we analyzed clinical features and long-term follow-up clinical data of this infection in children. Methods : Forty-seven cases of inpatients were diagnosed...
Central Diabetes Insipidus in Children Related to Craniotomy for a Brain Tumor
Seung Mi Song, Eun Jung Park, Jung Sim Kim, Hong Hoe Koo, Mun Hyang Lee, Hyung Jin Shin, Dong Kyu Jin
Clin Exp Pediatr. 1999;42(12):1702-1710.   Published online December 15, 1999
Purpose : Diabetes insipidus(DI) has been known to be a relatively common complication after craniotomy. We have investigated the incidence and clinical course of DI in children related to craniotomy for a brain tumor and determined the risk factors of postoperative DI. Methods : Sixty-two pediatric patients, who have undergone craniotomy for a brain tumor(including stereotactic biopsy) from February 1995 through...
Side Effects of Antiepileptic Drug in Children
Ick-Jin Song, Sang-Ook Nam
Clin Exp Pediatr. 1999;42(11):1559-1566.   Published online November 15, 1999
Purpose : The purpose of this study is to estimate the side effects of antiepileptic drug(AED) in children. Methods : Subjects were 267 children who had received AED for at least 1 month during January 1995 to July 1998. We reviewed their sex, age at start of seizure onset, age at medication, class and number of AED, developmental delay, type and...
Implication of vacA s1 Genotype of Helicobacter pylori in Children
Yae Jean Kim, Hae Young Park, Mi Ae Lee, Jeong Wan Seo
Clin Exp Pediatr. 1999;42(11):1516-1523.   Published online November 15, 1999
Purpose : Recently vacA s1 genotype of Helicobacter pylori was known to be associated with enhanced inflammation and peptic ulceration. To evaluate the association of the vacA s1 genotype with enhanced inflammation and peptic ulceration in children, we performed a polymerase chain reaction(PCR) for vacA s1 genotype. Methods : Twenty-seven CLO test-positive children were enrolled. They also revealed histological detection...
Serum Leptin Concentrations in Extremely Obese Childen
Yon Ho Choe, In Young Hyun
Clin Exp Pediatr. 1999;42(8):1136-1140.   Published online August 15, 1999
Purpose : The purpose of this study is to investigate whether there is a difference in leptin concentrations between those of children of normal weight and extremely obese children. Methods : We measured serum concentrations of leptin in 70 extremely obese subjects(7 to 12 years, 20 girls and 50 boys), whose serums had been frozen at -70℃. Height, weight, obesity index,...
Final Height in Idiopathic Growth Hormone(GH) Deficient Children Treated with GH
Byung Churl Lee
Clin Exp Pediatr. 1999;42(6):852-857.   Published online June 15, 1999
Purpose : Improved adult height is a major goal in the treatment of children with short stature due to GH deficiency(GHD). The purpose of this study was to evaluate final height in idiopathic GH deficient children after long-term GH treatment Methods : GHD was diagnosed in 9 male patients by at least two stimulation tests(maximum GH level≤5ng/ml). Other pituitary functions were...
Positivity of cagA and vacA Genes of Helicobacter pylori by PCR Assay of Gastric Biopsy Specimens and Gastric Inflammation in Children
Jeong Wan Seo, Mi Ae Lee, Woon Sup Ha
Clin Exp Pediatr. 1999;42(4):491-500.   Published online April 15, 1999
Purpose : The aim of the present study is to detect cagA and vacA genes of Helicobacter pylori(H. pylori) strain in gastric biopsy specimens and to evaluate its association with gastric inflammation in children. Methods : The cagA and vacA genes were detected by a direct polymerase chain reaction(PCR) assay of gastric biopsy specimens in 22 patients who were...
Changing Social Background Pattern of Children in Adoption Institutions(the 4th Report)
Hye Jeong Kim, Jin A Son, Jae Youn Kim, Don Hee Ahn
Clin Exp Pediatr. 1999;42(1):115-121.   Published online January 15, 1999
Purpose : A study was undertaken to assess the social background of abandoning children at adoption institutions. The results were compared to those of three previous reports from the institution. Methods : A total of 536 children who had been admitted to the institution during the period of 1993 to 1996 were subjected to the study. The medical records were...
Clinical and Endoscopic Findings in Children with Duodenal Ulcer due to Helicobacter pylori Infection
Hwa Jung Kim, Hae Jeong Han, Sang Gil An, Ji Sook Yoo, Hee Sup Kim, Hann Tchah, Ho Jin Park, Mi Kyoung Shin
Clin Exp Pediatr. 1999;42(1):69-76.   Published online January 15, 1999
Purpose : Recently, a wide application of gastrofiberoscopy in pediatrics has revealed that the incidence of peptic ulcer has increased in the past years, and various results were reported about the relationship between duodenal ulcer and H. pylori. The aim of this retrospective study is to investigate the role of H. pylori in duodenal ulcers in children and to help diagnose and treat duodenal...
A Clinical Analysis on Acute Lower Respiratory Tract Infections in Children Caused by Influenza Virus in Children
Kiehl Hyung Lee, Woo Kyung Kim, Mi Ran Kim, Dug Ha Kim, Hae Ran Lee, Chong Young Park, Kyu Man Lee
Clin Exp Pediatr. 1998;41(12):1623-1631.   Published online December 15, 1998
Purpose : Although annual epidemics occur, there are only a few clinical studies on influenza in Korea. We evaluated the epidemic and clinical features of acute lower respiratory tract infections in children by influenza virus. Methods : From Feb., 1995 to July, 1997, influenza virus isolations and clinical review were performed on hospitalized children with acute lower respiratory tract infections at...
Compliance with Anticonvulsant Therapy in Epileptic Children
Young Hwan Choi, Ki Sik Min, Jong Wan Kim, Ki Yang Yoo
Clin Exp Pediatr. 1998;41(11):1553-1558.   Published online November 15, 1998
Purpose : Good compliance with an anticonvulsant medication regimen is essential for the successful management of epilepsy. However, pediatric compliance with anticonvulsant therapy did not well be studied. The aim of this study was to identify the following key in noncompliance in pediatric out patients receiving anticonvulsant therapy determining factors. Methods : Eighty-one epileptic outpatients under fifteen years of age with...
Clinical Features and Endoscopic Findings of Helicobacter pylori Infection in Children
Seon Hee Kim, Cheol Ho Chang, Churl Young Chung
Clin Exp Pediatr. 1998;41(10):1359-1364.   Published online October 15, 1998
Purpose : Helicobacter pylori(H. pylori) is recognized as the cause of primary or unexplained gastrointestinal diseases in children as well as in adults. However, it is unclear whether H. pylori causes specific clinical symptoms or diseases. Therefore, we studied the clinical manifestations associated with H. pylori infection in consecutive symptomatic children undergoing diagnostic endoscopy. Methods : This study included 42...
Prevalence and Clinical Features of Wolff-Parkinson-White(WPW)- Type Ventricular Preexcitation Syndrome in Children
Byung Ju Kim, Jae Sook Ma
Clin Exp Pediatr. 1998;41(9):1243-1249.   Published online September 15, 1998
Purpose : This study was conducted to establish the prevalence and clinical features of WPW- type ventricular preexcitation syndrome in children. Methods : Eighteen patients were discovered by the mass heart disease screening using ECG on 47,691 elementary school children in Kwangju from September 1992 to December 1994(group 1), and 14 patients were diagnosed at the Department of Pediatrics, Chonnam...
A Clinical Study on Acute Lower Respiratory Tract Infections by Adenovirus in Children
Ui Chong Chong, Mi Ran Kim, Dug Ha Kim, Hae Ran Lee, Chong Young Park, Han Sung Kim, Kyu Man Lee
Clin Exp Pediatr. 1998;41(8):1070-1077.   Published online August 15, 1998
Purpose : This study was performed to characterize the epidemiologic and clinical features of acute adenoviral lower respiratory tract infections. Methods : Culture and indirect immunofluorescence for adenovirus was done with nasopharyngeal aspirates from patients with acute lower respiratory tract infections from April to September, 1996. Cultured virus was serotyped for type 3, 4, and 7a by neutralization test, and medical...
A Study for Causes of Death in Korean Children
Ha Baik Lee, Jun Hee Sul, Young Yull Koh, Jong Wan Kim, Young Jin Hong, Nam Su Kim, Myung Ik Lee
Clin Exp Pediatr. 1998;41(8):1047-1059.   Published online August 15, 1998
Purpose : Analyzing of the causes of childhood death will provide us with the basis to understand prevalent diseases and to make the best possible health plan according to the studies. The National Statistical Office(NSO) of Korea has released an annual report of nationwide death. However, it could have underestimated the death toll of children because of delayed or missing...
Serum Leptin Concentrations in Korean Children
Yon Ho Choe, Soon Ki Kim, Young Hyun
Clin Exp Pediatr. 1998;41(7):960-965.   Published online July 15, 1998
Purpose : Leptin is the product of the ob gene secreted by adipocyte. This study investigated whether leptin concentrations were elevated in obese children and the relationship between leptin concentrations and gender, and age in Korean children. Methods : We measured serum concentrations of leptin in 124 subjects(10 to 18 years, 62 girls and 62 boys). Height, weight, obesity index, and...
Serum Leptin Levels in Obese Children
Kyoung Ah Ha, Il Ran Kim, Mi Jung Park, Jae Heon Kang, Churl Young Chung
Clin Exp Pediatr. 1998;41(7):953-959.   Published online July 15, 1998
Purpose : Leptin is a protein encoded by the ob gene that is expressed in adipocytes. It regulates eating behavior by the action to the satiety centers in the hypothalamus. In ob/ob mouse, adipocytes can not produce leptin because of a mutation in the ob gene which results in obesity. Whereas, leptin concentrations were elevated in obese adults, and leptin...
Pollen Allergy in Children(Ⅱ) : The Significance of Tree Pollen As a Causative Allergen in Children with Allergic Diseases
Soo-Young Lee, Jeong-Soe Park, Ki-Sun Lee, Chang Ho Hong
Clin Exp Pediatr. 1998;41(6):799-807.   Published online June 15, 1998
Purpose : The positive rates of allergy skin test of pollens are relatively higher in children in Suwon compared to other areas in Korea. To evaluate the significance of tree pollen as a causative allergen, we undertook this study. Methods : In 252 children with asthma, scratch tests were done with 72 extracts, including 9 tree pollen. Antigen specific serum IgE antibodies were measured...
Clinical Characteristics of Complex Partial Seizures : a Temporal versus a Frontal Lobe Onset
Joon Soo Lee, Jae Hyun Park, Chang Jun Coe
Clin Exp Pediatr. 1998;41(6):769-774.   Published online June 15, 1998
Purpose : This study was performed to correlate clinical behaviours with either a temporal or frontal site of origin and then to identify behaviours that might have a significant practical value in differentiating a temporal from a frontal focus and thus reduce the need for invasive monitoring. Methods : We analysed 129 seizures that occured during video-EEG monitoring in 13 patients with temporal lobe epilepsy(TLE)...
Acute Renal Failure in Children : Underlying Disease and Management according to Age
Eun Joung Park, Joung Sim Kim, Jai Bok Yoo, Joung Sook Sul, Si Whan Koh, Phil Soo Oh, I Suk Kang, Moon Soo Park, Heung Jae Lee, Dong Kyoo Jin
Clin Exp Pediatr. 1998;41(5):654-662.   Published online May 15, 1998
Purpose : It has been stressed that age itself as well as multiple organ failure are important prognostic factors in acute renal failure(ARF) in children. This study was performed to find out the significance of age factor and underlying disease of ARF in children. Methods : We tried to review 58 pediatric ARF cases, retrospectively, in the pediatric intensive care unit(excluding...
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