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Case Report
Acquired Persistent Cytomegalovirus Infection : An Association with Common Variable Immunodeficiency
Min Hyea Kim, Young Mi Hong, Sung Joo Lee, Je Geun Chi, Dong Soo Kim
Clin Exp Pediatr. 1992;35(9):1272-1279.   Published online September 15, 1992
Acquired persistent cytomegalovirus infection was diagnosed by anti CMV antibody and lymph node biopsy and persisted in a 3-year-old boy with recurrent episode of high fever, lymphadenopathy hepatosplenomegaly and pneumonia. Initial immunologic abnormalities including low serum IgG, high IgM decreased T4 and T4/T8 ratio finally progressed to immunologic paralysis which was compatible to common variable immunodeficiency. This is the first case which...
Transfusion-Acquired Cytomegalovirus Infections in Two Premature Infants
Dong Wook Kim, Kyung Un No, Mi Jung Kim, Soon Mee Park, Hee Sup Kim, Young Pyo Chang, Hoan Jong Lee, Jung-Hwan Choi, Chong Ku Yun, Je Geun Chi
Clin Exp Pediatr. 1992;35(8):1141-1147.   Published online August 15, 1992
Transfusion-acquired perinatal cytomegalovirus (CMV) infection can cause significant morbidity and mortality, particularly in premature infants with a birth wight of less than 1,500 gm. This recognizable syndrome consisted of deterioration of respiratory function, hepatosplenogaly, unusual gray pallor with disturbing septic appearance, lymphocytosis, thrombocytopenia and hemolytic anemia. We experienced transfusion-acquired CMV infections in 2 premature infants with a birth weight of...
Original Article
Clinical Study of Group B Streptococcal Infection in Infants Less Than Two Months of Age
Hee Jeong Ahn, Ji Yeon Lim, Sung Hee Oh, In Joon Seol, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1992;35(1):17-25.   Published online January 15, 1992
Since 1970, the group B streptococcus has become significant cause of neonatal septicemia and/or meningitis, in recent years the group B streptococcus and E.coli are most common etiologic agent of septicemia and/or meningitis in infants less than two months of age. We have analized 8 cases of group B streptococcal infection who admitted to the department of Pediatrics, Hanyang University...
Congenital cytomegalovirus infection: incidence and clinical outcome.
Young Mo Sohn, Kook In Park, Chul Lee, Dong Kwan Han, Won Young Lee
Clin Exp Pediatr. 1991;34(10):1365-1372.   Published online October 31, 1991
In order to assess the rate of congenital cytomegalovirus (CMV) infection in newborns, CMV IgG antibody was studies at about 37.5 weeks gestation in 309 mothers and a positive rate of 96.4% was obtained. Virus culture for CMV from urine of 514 neonates less than 1 week after birth resulted in CMV growth in 6 neonates showing a 1.2% congenital infection rate. In...
A case of nephrogenic diabetes insipidus due to vesicoureteral reflux.
Yong Bae Suh, Jong Yul Jeon, Sung Ho Cha, Byoung Soo Cho, Chang Il Ahn
Clin Exp Pediatr. 1991;34(9):1299-1304.   Published online September 30, 1991
Nephrogenic diabetes insipidus is a disorder characterized by polydipsia and polyuria resulting from failure of the renal tubules and collecting ducts to respond to antidiuretic hormone despite elevated blood levels of antidiuretic hormone. We experienced a case of nephrogenic diabetes insipidus in 13 months-old girl probably secondary to vesicoureteral reflux grade IV. The clinical manifestations were extreme thirst, polydipsia and polyuria. Family history was nonspecific and...
The diagnostic significance of APR score in early detection of neonatal bacterial infection.
Ki Won Park, Kyeong Choi, Young Youn Choi, Tai Ju Hwang
Clin Exp Pediatr. 1991;34(9):1223-1230.   Published online September 30, 1991
An accurate and rapid diagnostic test is essential in the management of bacterial infection in neonates because they lack specific symptoms and the bacterial infections in neonates tends to have rapid progression and poor prognosis. As for the method, APR (acute phase reactants), a score measuring C-reactive protein (CRP), 상racid glycoprotein (이-AG) and Haptoglobin (Hp) by latex agglutination seems to be one of promising methods. In...
A case of pancytopenia associated with mycoplasmal pneumonia.
Young Mee Yoo, Beom Soo Park, In Sang Jeon, Hee Young Shin, Hyo Seop Ahn, Se Jung Sohn
Clin Exp Pediatr. 1991;34(6):826-831.   Published online June 30, 1991
Mycoplasma pneumoniae infection is manifestated as pneumonia and extra-pulmonary symptoms such as hematologic, neurologic, gastrointestinal, musculoskeletal, dermatologic and cardiac manifes- tations. Among the hematologic changes, hemolytic anemia is most frequently seen. Throm- bocytopenic purpura, lymphocytosis or rarely lymphopenia, elevated erythrocyte sedimentation rate, positive direct Coombs test, reticulocytosis and DIC are known hematologic features. This 12 years old female patient was presented with pneumonia and pancytopenia....
A case of hyperimmunoglobulin E syndrome.
Myeong Cheol Shinn, Sung Dong Choi, Byung Gyu Suh, Jin Han Kang, Joon Sung Lee
Clin Exp Pediatr. 1991;34(2):292-298.   Published online February 28, 1991
The hyperimmunoglobulin E syndrome is a primary immunodeficiency disorder characterized by serious recurrent bacterial infections of the skin and respiratory system in early life, and markedly elevated serum IgE level. These recurrent infections are generally subcutaneous abscesses caused by Staphylococcus aureus. Also, additional characteristrics of this syndrome include coarse facial appearance, chronic pruritic dermatitis and eosinophilia. The baisic immunologic defect mechanism in hyperimmunoglobulin E syndrome is...
A clinical and bacteriologic study of infants and children with urinary tract infection.
Jae In Roh, Yeong Su Kwon, Hung Kun Oh, Jin Hee Jeong, Man Chul Ha, Jin Yeong Jeong
Clin Exp Pediatr. 1991;34(1):57-65.   Published online January 31, 1991
Clinical, Bacteriologic and radiologic studies were performed in 321 infants and childen with urinary Tract Infection who were diagnosed at Department of pediatrics, Haesung Hospital from Jan. 1984 to Dec. 1988. The results were summarized as follows: 1) The incidence of urinary tract infection was highest in children below the age of one year, the rate then decreased with age. Among the total 321 cases,...
Congenital Cytomegalovirus infection.
Kang Woo park, Ho Seek Ahn, Eui Bon Koo, Sung Won Kim, Kil Hyun Kim
Clin Exp Pediatr. 1990;33(9):1271-1275.   Published online September 30, 1990
We report a case of congenital cytomegalovirus infection that was associated with microcephaly, hydrocephalus and periventricular calcification. The male baby was born after 39wks gestation to 28 year-old mother who had no prenatel problem except for active pulmonary tuberculosis and pre- mature rupture of membrain. Hydrocephalus was recognized by antenatal ultrasonography at 8 weeks of geststional age and microcephaly was noted at birth. This enable...
Relationship between anaphylactoid purpura and Beta-Hemolytic Streptococcal Infection.
Ji Eun Lee, Young Sook Kang, Joon Sik Kim, Sung Ho Kim, Chin Moo Kang
Clin Exp Pediatr. 1990;33(9):1231-1236.   Published online September 30, 1990
Relationship between anaphylactoid purpura and beta-hemolytic streptococcal infection was obser- ved and analyzed through clinical manifestation and labortory findings in 146 cases of allergic purpura, hospitalized at Dongsan hospital, Keimyung University during the period from January, 1981 to May, 1987. The following results were obtained. 1) The age distribution of anaphylactoid purpura showed a peak incidence between 2 to 7 years of age and male preponderance was...
Comparison of the 3-Imaging Procedures (IVP,VCUG & USG) on Children with Urinary Tract Infection.
Min Hee Yeo, Won Yeob Kim, Jee Sung Kim, Sang Geel Lee, Im Ju Kang
Clin Exp Pediatr. 1990;33(3):332-340.   Published online March 31, 1990
This study was performed in 106 childrens with urinary tract infection who were admitted to Pediatric Department of Fatima Hospital during 2 1/2 years period from January 1986 to June 1988. Each patient was evaluated in three imaging procedures: intravenous pyelography (IVP), voiding cystourethrography (VCUG) and ultrasonography (USG). 1) Of 106 cases, 59 cases (55.7%) were normal on the three imaging procedures (IVP, VCUG, USG), whereas...
A Study on Anemia of Acute Infectious Disease in Children.
Hae Won Lee, Young Mi Hong, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1990;33(1):75-80.   Published online January 31, 1990
The anemia of acute infectious disease has come to attention recently, since iron deficiency anemia has decreased. We screened for anemia in children admitted to Ewha Womans University Hospital due to acute infectious disease between January 1, 1986 and July 31, 1988, and studied the incidence and characteristics of anemia in acute infectious diseases. The result were as follows: 1) The incidence of anemia in acute...
A Clinical Study of Infants and Children with Urinary Tract Infection.
Hyoung Doo Lee, Chan Yung Kim
Clin Exp Pediatr. 1989;32(12):1706-1714.   Published online December 31, 1989
Clinical, bacteriologic and radiologic studies were performed in 63 infants and children with urinary tract infection who were admitted to Department of Padiatrics, Pusan National University Hospital from March 1982 to February 1988. The results were summarized as follows: 1) UTI was more prevalent in infancy and early childhood (71.4%). Sex distribution was similar in all age group, and male was more prevalent in infancy and...
Asymptomatic human rotavirus infections during infancy and preschool period.
Hye Lim Jung, Byoung Hoon Yoo, Tae Sub Shim
Clin Exp Pediatr. 1989;32(11):1482-1488.   Published online November 30, 1989
Asymptomatic human rotavirus (HRV) infection rate was studied by comparing the rate of HRV excretion in diarrhea cases with that in nondiarhea group of children under preschool age. HRV antigen in stool was detected by enzyme-linked immunosorbent assay (ELISA) from children under 6 years of age who were admitted to Pediatric Department of Chung-Ang University Medical Center from November 1988 to mid-April 1989. 1) HRV antigen...
A study of neonatal cholestasis and cytomegalovirus infection.
Moon A Kim, Ki Sup Chung
Clin Exp Pediatr. 1989;32(11):1474-1481.   Published online November 30, 1989
A clinical assessment of 25 patients with neonatal cholestasis caused by cytomegalovirus infection who were admitted to the Department of Pediatrics, Yonsei University College of Medicine from January 1983 to July 1988 was performed. The results were as follows: 1) The patients with neonatal cholestasis caused by cytomegalovirus infection were 19% of the total patients with neonatal cholestasis from January 1983 to July 1988 and were...
Urinary Tract Infection Caused by Escherichia coli.
Sung Oh Kim, Sun Yang Hong, Woo Gill Lee
Clin Exp Pediatr. 1989;32(7):972-977.   Published online July 31, 1989
Among 223 cases who were admitted to the Department of Pediatrics, Hanyang University Hospital from January 1980 to December 1987 under the diagnosis of Urinary Tract Infection(UTI), 132 cases of E. coli UTI were compared with 91 cases of non-E. coli UTI by age, sex distribution, clinical manifestation, laboratory results and clinical course. The results obtained were as follows: 1. There were no significant differences of...
Radiologic Evaluation About Urinary Tract Infection In Children.
Soon Wha Kim, Byung Rai Cho, Don Hee Ahn, Keun Chan Sohn, Chong Hyun Yoon
Clin Exp Pediatr. 1989;32(6):797-803.   Published online June 30, 1989
There had been total 165 cases of urinary tract infection who had been admitted to the ward of pediatrics, National Medical Center from ]an. 1986 to Sept. 1987. Among these, 80 cases had indication of radiologic evaluation; they were the first-documented urinary tract infection in male patients, the first documented urinary tract infection in female patients younger than 6 years of age,...
Infections in Childhood Leukemia.
Choong Won Lee, Young Sik Kim, Byung Kyu Park, Soon Ki Kim, Il Soo Ha, Hoan Jong Lee, Hyo Seop Ahn
Clin Exp Pediatr. 1989;32(5):659-664.   Published online May 31, 1989
A retrospective study was performed on twenty-nine children, who had experienced infection one or more times, among the thirty-eight children diagnosed as leukemia at the Department of Pediatrics, Seoul National University Hospital, between January, 1984 and June, 1985, and followed up for more than three years. The results were as follows; 1) The age of patients ranged from I year 5 months to 14 years...
Vesicoureteral Reflux Associated with Urinary Tract Infection in Children.
Kee Hyuck Kim, Hong Kyu Lee, Soon Il Lee, Moon Chul Kim
Clin Exp Pediatr. 1989;32(5):638-643.   Published online May 31, 1989
The vesicoureteral reflux(VUR) is frequently found among the patients with urinary tract infection(UTI) and progress to reflux nphropathy and even renal failure. So, early detection and pr er treatment are important to prevent renal damage. The authors studied 221 patients with UTI admitted at Sowha children’s hospital from January, 1985 to June, 1988. Intravenous pyelography and voiding cystourethrography were performed in all patient with UTI. The...
A Case of Mycoplasmal Meningitis Associated with Mycoplasma Pneumoniae Pneumonia.
Sang Young Jeong, Seung Koog Kim, Sung Ho Cha, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(4):556-560.   Published online April 30, 1989
Mycoplasmas have been recognized as pathogens of respiratory tract in children and adolescence, but clinically apparent pneumonia develops in only 3 to 10% of infected persons. Central nervous system complication, such as aseptic meningitis, meningoencephalitis. transverse myelitis, hemiplegia, cerebellar ataxia and psychosis, associated with Mycoplasma pneumoniae infection were developed in .0.1 % of all Mycoplasmal infection. We experienced a case of Mycoplasma pneumoniae pneumonia and...
Clinical Studies of Urinary Tract Infection in Infant and Children.
Kee Sung Yang, Mi Soo Ahn, Hong Bae Kim, Ji Sub Oh
Clin Exp Pediatr. 1989;32(4):533-541.   Published online April 30, 1989
Clinical studies on the 82 patients of sympomatic urinary tract infection who were admitted to pediatric department of Wallace Memorial Baptist Hospital from August 1984 to July 1987 were subjected in this study. The result were as follows. 1) The incidence was 0.79% of total pediatric inpatients during the same period. 2) Age incidence disclosed under 1 year in 49 patients(59.7%) and under 6 year...
Changes of Antimicrobial Susceptibilities of Bacteria Isolated from Clinical Specimens During Recent Four Years.
Byung Rai Cho, Young Jin Hong, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1989;32(2):165-179.   Published online February 28, 1989
From Jan,M 1983 to Dec., 1986, we studied total 2386 microorganisms which were isolated from various clinical specimens of admitted patients and out-patients in the department of pediatrics, NMC, and their antimicrobial susceptibilities were compared. The results were as follows; 1) The most frequently isolated stains from various specimens were S. aureus from throat, E. coli from urine, Shigella from stool, S. aureus from blood,...
Urinary Tract Infection in Febrile Infants.
Jung Soon Whang, Seung Hee Choi, Seong Joo Lee, Keun Lee
Clin Exp Pediatr. 1989;32(1):45-51.   Published online January 31, 1989
Uninary tract infection as one of the common infectious disease all through the childhood and can be the cause of febrile illnesses. During infancy, the diagnosis of UTI is easily overooked because of relative lack of charateristic urinary symptoms. But UTI was found to cause longterm sequelae more often in infancy than later. We studied 258 cases of febrile infants and 345 cases of...
A Clinical Study of Hospitalized Neonates with Fever.
Youn Mo Ahn, Chang Ryul Kim, Woo Gill Lee, Soo Jee Moon
Clin Exp Pediatr. 1988;31(11):1437-1444.   Published online November 30, 1988
Life-threatening bacterial infections such as meningitis, septicemia, and pneumonia in the neonates are more common than at any other time in life and signs of these infections are often subtle and non-specific. Because of these factors, the patient who has persistent fever will almost always be started on parenteral antibiotics immediately following evaluation. On the other hand there is also evidence that the hospital...
A Case of Tsutsugamushi Disease.
Tae Kyu Hame, Soo Chun Kim, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1988;31(8):1048-1053.   Published online August 31, 1988
Rickettsial infection has not been identified in Korea since about 20-30 years before in Korea. However, there has been an increasing incidence of Tsutsugamushi disease in recent years. Tsutsugamushi disease is a variety of rickettsial infection to human causing abrupt onset of fever, headadie, vomiting, myalgia, and abdominal pain. In severe case, causing D.I.C., pulmonary edema, hypoalbuminemia and generalized edema. We reported a case of...
A Case of 18P-Syndrome with Frequent Intection.
Ellen A Kim, Jong Sung Eum, Hee Ju Kim, Sung Ill Ahn, Kyung Yu Park
Clin Exp Pediatr. 1988;31(3):370-374.   Published online March 31, 1988
We herein reported a case of newborn with round face, low nasal bridge, micrognathia, down turning comers of mouth, large protruding ears, high arched palate with webbed short neck: This odd looking newborn was confirmed to have deltion of short arm of chromosome 18 (18P- syndrome). Frequent episodes of pneumonia developed until recently at 6 months of age. The cause of this frequent infection...
Sex and Age Differences of Etiologic Organisms in Urinary Tract Infection.
Sun Ho Lee, Seung Jae Yang, Jeh Hoon Shin, Woo Gill Lee
Clin Exp Pediatr. 1987;30(10):1100-1106.   Published online October 31, 1987
There is suggestive evidence that natural history of urinary tract infection (UTI) in male children differs from that of the disease in female children. We have studied sex and age differences of etiologic organism in 257 patients with UTI who were admitted to the Department of Pediatrics Hanyang University Hospital from January 1978 toDecember 1985. All patient had the positive urine culture and a...
Clinical Value of Urinary β₂ -Microglobulin in Patients with Urianry Tract Infection.
Nak Uk Sung, Chang Ryul Kim, Jeh Hoon Shin, Woo Gill Lee
Clin Exp Pediatr. 1987;30(9):1014-1020.   Published online September 30, 1987
Urinary tract infection (UTI) in children is relatively common infectious disease and it may be the forerunner of severe renal diseases in adulthood. The site of infection is an important factor in the evaluation of the clinical course, treatment and prognosis of patients with UTI, because patients with bacteriuria of renal origin (pyelonephritis) are probably at risk of developing the renal parenchymal reduction seen...
Clinical Studies of Urinary Tract Infection in Infant and Children.
Bo Kyung Cho, Jeong Oh Kim, Ik Jun Lee
Clin Exp Pediatr. 1987;30(1):64-70.   Published online January 31, 1987
Clinical studies on the 42 cases of urinary tract infection who were admitted to Pediatric department of Kangnam St. Mary’s Hospital from January 1982 to December 1985 were subjected in this study. The results were as follows: 1) The incidental ratio to total inpatients was 0.76%. 2) Age incidence disclosed under 1 year in 10 cases (23.8%), 1 to 6 year in 21 cases(50%), 7...
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