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Original Article
The Assessment of Pulmonary Parenchymal Damage in Congenital Heart Disease using Lung Perfusion Scan
Hong Ryang Gil, Jae Goo Lee, Kang Uk Lee, Eun Ho Yi, Myung Ja Yun, Chung Il Noh, Jung Yeon Choi, Yong Soo Yun
Clin Exp Pediatr. 1998;41(5):640-645.   Published online May 15, 1998
Purpose : In acyanotic congenital heart disease of children with left to right shunt, 99mTc- Macroaggregate albumin(MAA) was employed to determine the scintigraphic severity of pulmonary parenchymal damage. Methods : These data of lung perfusion scan using 99mTc-MAA were compared with hemodynamic values obtained from cardiac catheterization. Results : The mean Pulmonary arterial pressure(≥30mmHg), total pulmonary resistance(≥2 Wood unit)...
Incidence of Congenital Heart Disease in Neonate by Color Doppler Echocardiography
Tae Chan Kwon, Joon Sik Kim, Sang Lak Lee, Myung Sung Kim, Geun Soo Park, Chun Soo Kim, In Joo Kim, Bin Ahn
Clin Exp Pediatr. 1998;41(3):363-368.   Published online March 15, 1998
Purpose : Many reports exist about the frequency of congenital heart disease(CHD) in the world, but according to the definition of CHD and subjects of study group, many differences existed between the reports. We conducted this study to evaluate the incidence and frequency of CHD by color Doppler echocardiography in neonate, and to suggest a preliminary model of incidence of...
Congenital Heart Disease and Associated Extracardiac Anomalies in Autopsies
Soon Seong Park, Myeong Ja Yoon, Jeong Sun Kim, Jeong Wook Seo, Chung Il Noh, Jung Yun Choi, Yong Soo Yoon, Byung Il Kim, Joong Hwan Choi, Chong Ku Yoon
Clin Exp Pediatr. 1998;41(3):354-362.   Published online March 15, 1998
Purpose : In order to find out how frequently and what kind of extra-cardiac anomalies (CAs) is associated with congenital heart disease(CHD) in general and in each CAs, autopsies with congenital cardiovascular malformations were studied. Methods : Autopsy files of Seoul National University Children' s Hospital from 1991 to 1995 were reviewed to find cases of CHDs. Other extra-CAs were tabulated from the records...
Recent Trend of Increasing Proportion of Interventional Catheterization in Congenital Heart Disease
Sang Yup Lee, Mi Jung Kang, Eun Jung Bae, In Seung Park, Woo Sup Kim, Se Jung Sohn, Seong Ho Kim
Clin Exp Pediatr. 1997;40(4):512-518.   Published online April 15, 1997
Purpose : The proportion of interventional catheterization in congenital heart disease is being increased in Korea, especially in Sejong Heart Institute, so we performed statistical analysis on the cardiac catheterization cases. Methods : Total 233 cases of congenital heart disease confirmed by cardiac catheterization at the Sejong Heart Institute between Jaunary 1995 and June 1995 were analyzed retrospectively. Results : 1) The...
Diagnosis and Treatment of Fetal Cardiac Anomalies
Nam Su Kim, Myung Kul Yum, Hahng Lee, Sung Ro Jung, Jung Bae Yoo, Jae Ek Lee
Clin Exp Pediatr. 1996;39(10):1395-1404.   Published online October 15, 1996
Purpose : Fetal echocardiography is used for the prenatal diagnosis of congenital heart disease. Fetal echocardiography allows decisions to be made in advance where the fetal abnormality is not compatible with life after delivery or where early correction is required. Our fetal echocardiographic experience was analysed retrospectively to guide future clinical application. Methods : 138 mothers had fetal echocardiography from April 1992 to December...
The Effects of Lipo Prostaglandin E1(EglandinⓇ) in Patients with Ductus Dependent Congenital Heart Disease
Sejung Sohn, Seong Ho Kim, Eun Jung Bae, In Seung Park
Clin Exp Pediatr. 1996;39(8):1111-1121.   Published online August 15, 1996
Purpose : The adverse reactions of prostaglandin E1(PGE1) are troublesome in the preoperative management of critical patients with ductus dependent congenital heart disease, and a preparation with less adverse reactions is preferable. The effects of Lipo PGE1, a new preparation of PGE1 contained in lipid microspheres, were compared with those of conventional PGE1(PGE1-CD). Methods : Lipo PGE1 was infused at a rate of 5...
Case Report
An Autopsy Case of Double Aortic Arch
Ji Sook Kim, Yong Myung Jo, Kyung Hee Ko, Eun Ryoung Kim, Je Grun Chi
Clin Exp Pediatr. 1996;39(5):727-731.   Published online May 15, 1996
Double aortic arch is the most common type of symptomatic vascularring. In most patients, the symptoms are manifested at birth or in early infancy. Double aortic arch usually has more severe symptoms than other types of complete vascular rings. We experienced one case of complete duplicated double aortic arch with left descending aorta and left patent ductus arteriosus. A one-day-old female neonate was transferred...
Original Article
Changes of Clinical Patterns of the Acute Rheumatic Fever in Korea(Compared report of 1973-1985 with that of 1986-1992)
Hye Sun Yoon, Min Young Park, Wan Young Shin, Byong Soo Sco, Sung Ho Cho
Clin Exp Pediatr. 1995;38(4):470-481.   Published online April 15, 1995
Purpose : The annual incidence of acute rheumatic fever in Korea was not changing during 1980 to 1989 from Nationwide survey in 1991 in spite of talking about scanty outbreak among doctors in recent year.The proportion of patients with acute rheumatic fever among the entire pediatirc inpatients each year was approximately 0.3% and did not change significantly throughout the...
Clinical Studies on Congenital Heart Diseases
Kyeong-Ah Lee, Tae-Guen Song, Hyun-Kee Chung
Clin Exp Pediatr. 1994;37(4):472-480.   Published online April 15, 1994
The clinical studies were performed on 304 patients with heart disease who had been received corrective heart surgery at Kosin Medical Center from July, 1984 to December, 1991. The results were follows : 1) Out of 304 patients, 162 cases (53.3%) were male and 142 cases (46.7%) were female and sex ratio was 1.15 : 1.35 cases (11.5%) had clinical cyanosis and...
Case Report
A Case of Congenital Tricuspid Stenosis
Chan Uhng Joo, Soo Young Cho, Soo Chul Cho
Clin Exp Pediatr. 1993;36(5):733-736.   Published online May 15, 1993
Congenital tricuspid stenosis is ancommon congenital heart anomaly. Tricuspid stenosis is usually associated with other anomalies, most commonly severe pulmonary stenosis or atresia with secondary hypoplasia of the right ventricle. Clinically it may be difficult to distinguish from tricuspid atresia. A case of congenital tricuspid stenosis in a 32 day-old-girl is presented. The patient had cyanosis and dyspnea. Echocardiographic study revealed...
A Case of Cerebrocostomandibular Syndrome with Congenital Heart Disease
Sang Heui Song, Kook In Park, Hye Jung Joo, Ran Namgung, Chul Lee, Dong Gwan Han
Clin Exp Pediatr. 1993;36(4):574-578.   Published online April 15, 1993
Cerebrocostomandibular Syndrome is characterized by micrognathia, cleft palate, multiple thorax deformity and frequently, mental deficiency. Respiratory compromise is a common cause of death. We experienced a case of cerebrocostomandibular syndrome with congeniyal heart disease in a 2 day old female baby with the chief complaint of cyanosis and respiratory difficulty since birth, She was delivered by cesarian section due to delayed...
Original Article
A Clinical Study on Cardiovascular Disease of Children Taken Cardiac Catheterization and Cineangiography
Gi Yeon Song, Seog Beom Cho, Pyoung Han Hwang, Chan Uhng Joo, Jung Soo Kim
Clin Exp Pediatr. 1992;35(7):949-956.   Published online July 15, 1992
A clinical study was made on 533 patients with cardiovascular disease who were admitted to pediatric department of Chonbuk National University Hospital and performed cardiac catheterization and cineangiography from February 1984 to August 1991. The results were as follows; 1) The ratio of male to female was about 0.81:1; among 533 cases, male 283cases, male 283cases, female 295cases. 2)The age distribution of the...
Erratum
Analysis of 5,653 Cases with Congental Heart Disease (CHD) Catheterized at Yonsei Medical Center - A 28-Year Review -
Dong Shik Chin, Jong Kyun Lee, Jun Hee Sul, Sung Kyu Lee, Bum Koo Cho
Clin Exp Pediatr. 1992;35(2):143-156.   Published online February 15, 1992
This is a 28-year analysis of 5,653 cases with congenital heart disease who underwent cardiac catheterization at Yonsei Medical Center from 1964 to 1991. Form 1964, there was a steady increment in the number of catheterized cases with CHD until the late 1970's when the patients population began to increase rapidlly. This was undoubtedly set off by the introduction of the...
Original Article
The Study on Extracardiac Anomalies Associated with Congenital Heart Diseases
Kye Hwan Seol, Kang Won Lee, Chang Sung Son, Joo Woo Lee, Young Chang Tockgo
Clin Exp Pediatr. 1992;35(1):26-33.   Published online January 15, 1992
or vice versa. But any specific association pattern of anomalies have remained unestablished despite of many researcherss efforts. Knowledge of the likely association of CHD and extracardiac anomalies may allow us to expect certain disturbances and to correct them, and lower the mortality and morbidity rates in children with CHD. The authors conducted this study in the hope of establishing...
Blade atrial septostomy in infants with cyanotic congenital heart diseases.
In Sook Park, Young Hwue Kim, Chang Yee Hong
Clin Exp Pediatr. 1991;34(12):1655-1663.   Published online December 31, 1991
In patients with certain types of congenital heart malformations, an adequate interatrial communi- cation is essential for survival and balloon atrial septostomy (BAS) is a life saving procedure in these infants. However, BAS alone is not successful in older infants and children with thickened atrial septum, and blade septostomy is indicated in these situations. This procedure so far has not been reported in Korean literature...
Balloon atrial septostomy through umbilical vein approach using flexible guide wire and sheath technique.
In Sook Park, Ki Soo Kim, Chang Yee Hong, Shi Joon Yoo
Clin Exp Pediatr. 1991;34(9):1294-1298.   Published online September 30, 1991
Balloon atrial septostomy is accepted as the best initial palliative treatment in infants with certain types of cyanotic congenital heart disease and the importance of prompt creation of atrial communi- cation can not be overemphasized in these patients. Balloon atrial septostomy is performed through femoral vein using percutaneous technique in most cases and is rarely done by cut down approach. However, percutaneous femoral vein...
The value of 2-D echocardiography in diagnosis of CHD.
Sang Kyung Yun, Young Woon Baek, Hyun Ki Jung
Clin Exp Pediatr. 1991;34(5):662-667.   Published online May 31, 1991
Cardiac catheterization, cineangiography and surgical analysis of 220 cases of congenital heart disease diagnosed by 2-D echocardiography was made, retrospectively from mar. 1985 to sep. 1989, who were admitted to the department of pediatrics Kosin Medical College Hospital. The results were analysed as follows; 1) 22 cases of 23 were correctly diagnosed in ASD, sensitivity and specificity of subxiphoid 2-D echocardiogram were 95.7% and 99.6% respectively. 2) 109...
A Clinical Study on Hematological Findings in Children with Cyanotic Congenital Heart Disease.
Seong Ho Kim, Heung Jae Lee, Hahng Lee
Clin Exp Pediatr. 1990;33(5):642-650.   Published online May 31, 1990
Children with cyanotic congenital heart disease (CCHD) and secondary polycythemia exhibit increased susceptibility to hemorrhage or thrombosis. The hemostatic disorder manifests itself by the occurrence of excessive hemorrhage after surgery, and by increased incidence of cerebrovascular accident of a thrombotic nature during life. To assess whether the severity of polycythemia in children with CCHD is correlated with coagula- tion abnormalities, hematologic studies with preoperative and...
Clinical Studies on Congenital Heart Diseases.
Hee Young Chun, Dae Churl Chung, In Kyung Sung, Kyong Su Lee, Du Bong Lee
Clin Exp Pediatr. 1990;33(1):66-74.   Published online January 31, 1990
A retrospective study of 10 years* experience with surgical treatment of congenital heart disease in the St. Mary’s Hospital from 1978 to 1987 was made. Data were analyzed on 188 children with congenital heart disease who had received corrective heart surgery under the age of 18 years. The results were as follows: 1) Out of 188 patients, ventricular septal defect(54.2% of all) was the most...
A Study on the Change of Plasma Renin Activity(PRA) and Aldosterone Concentration(PAC) before and after Heart Operation in Children with Congenital Heart Disease.
Jae Hong You, Jae Ho Lee
Clin Exp Pediatr. 1989;32(9):1232-1239.   Published online September 30, 1989
Thes is a study on changes of plasma renin activity (PRA) and aldosterone concentration (PAC) which was obtained before and after heart operation in 26 normotensive children with congenital heart diseases without renal disease admitted in Chungnam National University Hospital for cardiac catheterization with angiogram and heart operation from Apr. 1988 to Aug. 1988 to confirm any differences of PRA and PAC between groups...
Urinary Tract Anomalies in Congenital Heart Disease.
Chang Youn Lee, Young Seo Park, Hae Il Cheong, Jung Yun Choi, Young Soo Yun, Yong Choi, Kwang Wook Ko, In One Kim, Kyung Mo Yeun, Kwang Myung Kim, Hwang Choi
Clin Exp Pediatr. 1989;32(6):804-808.   Published online June 30, 1989
A variety of urinary tract anomalies were detected in 1,569 children with congenital heart disease during their cardiac evaluation with cardiac cineangiography in the Department of Pediatrics, Seoul National University Children’s Hospital within a period from October 1985 to April 1988. The incidence, nature and course of these urinary tract anomalies were analyzed and the results were as follows; 1) The number of male children...
Plasma Renin Activity (PRA) in Peripheral Vein and Renal Veins in Normotensive Children with Cyanotic Congenital Heart Disease.
Sang Kyu Park, Hae Il Cheong, Chung Il Noh, Yong Soo Yun, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1988;31(8):1021-1027.   Published online August 31, 1988
PRA’s in peripheral vein, both renal veins, and inferior vena cava (IVC) were measured in 25 normotensive children without renal disease undergoing cardiac catheterization for their underlying cyanotic congenital heart disease. And we presented the results as reference values/ranges of PRA in children. 1) There was no significant difference in PRA between both side renal veins at any absolute PRA levels with a mean ratio (RT/LT)...
Evaluation of Pulmonary and Systemic Blood Flow by Doppler Echocardiography in Pediatric Congenital Heart Disease.
Jae Hong Park, Chun Dong Kim, Jin Gon Jun
Clin Exp Pediatr. 1988;31(8):1014-1020.   Published online August 31, 1988
This study was designed to assess the accuracy of pulmonary (Qp) and systemic blood flow (Qs) and the ratio of pulmonary to systemic blood flow (Qp/Qs) measured by non-invasive range-gated pulsed Doppler echocardiography. Thirty five children with congenital heart disease, aged 4 months to 15 years, admitted for cardiac operation to this hospital, were studied. Cardiac outputs were measured by 2-dimensional range-gated pulsed Doppler...
Clinical Evaluation of Congenital Heart Disease in Down Syndrome.
Sang Kyu Park, Young Hoon Kim, Son Moon Shin, Chung Il Noh, Jung Yun Choi, Yong Soo Yun, Cang Yee Hong, Kyoo Wan Choi, Shin Yong Moon
Clin Exp Pediatr. 1986;29(10):1095-1103.   Published online October 31, 1986
The association of congenital heart disease in patients with Down syndrome has been recognized for nearly 100 years. A wide variety of congenital heart diseases have been identified in these patients. This is the report of clinical evaluation of 105 patients with congenital heart disease in Down syndrome, experienced at the Seoul National University Hospital, during past 6 years from Jan. 1980...
A Study of Radionuclide Angiocardiography in Congenital Heart Disease.
Beyong Sang Choi, Kyung Jin Shin, Beyong Sook Park, In Soo Choi, Chan Uhng Joo, Jung Soo Kim
Clin Exp Pediatr. 1986;29(9):964-968.   Published online September 30, 1986
In 101 heart disease patients, the radionuclide angiocardiography(RNA) were performed. Quantitation of left to right shunts were obtained by RNA and oximetry method in 41 patients simultaneously. A comparison of the values for Qp/Qs ratio obtained by RNA & oximetry in those patients revealed a good correlation coefficient of 0.87(P
Clinical Observation of Rheumatic Fever and Rheumatic Heart Disease in Children.
Soon Don Hong, Sung Ho Cha, Chang Il Ahn
Clin Exp Pediatr. 1986;29(6):596-603.   Published online June 30, 1986
Acute rheumatic fever is an inflammatory disease of the heart, joint, central nervous system, and subcutaneous tissues which developes after a nasopharyngeal infection by group A beta-hemolytic Streptococci. Rheumatic fever is especially important to pediatrician because of the most acquired heart disease which usually ensues. To analyze the 101 cases of rheumatic fever and rheumatic heart disease in pediatric department of...
A Case Report of Ventricular Septal Defect and Aortic Valve Insufficiency Occurred in Siblings.
K H Kim, S S Kim, J H Sul, S K Lee, D S Chin
Clin Exp Pediatr. 1985;28(4):386-389.   Published online April 30, 1985
The occurrence of congenital heart disease can be explained by genetic or environmental aspects. But these factors act separately only in about 10% and most of all, which reaches up to 90%, are inherited by the pattern of multifactorial inheritance, in which there is an underlying genetic predisition, usually produced by the small effects of many genes interacting with an...
Heart Disease Screening for Primary School Children.
Chang Yee Hong, In Sil Lee, Hee Ju Kim, Jung Hwan Choi, Hae Il Cheong, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1985;28(3):258-262.   Published online March 31, 1985
A heart disease screening program was performed on 15,685 primary school children in Seoul City from the first to sixth grade to estimate the prevalence of heart diseases. Among the 15,685 children examined, 45 were confirmed to have heart disease (2.9/1,000) Out of the 45 children, 38 had congenital heart disease(2.4/1,000) and 7 had rheumatic heart disease(0.4/1,000) and the ratio...
Echocardiographic Evaluation of Pulmonary Arterial Hypertension in Pediatric Congenital Heart disease.
Myoung Sung Moon, In Hee Park, Heung Jae Lee, Hahng Lee, Keun Soo Lee
Clin Exp Pediatr. 1984;27(10):971-981.   Published online October 31, 1984
To assess the validity of Echocardiographic criteria for pulmonary arterial hypertension we studied pulmonary valve motion in 75 congenital heart disease children. 75 patients were divided into two groups, A and B. The group A consisted of 39 patients who had normal pulmonary arterial pressure, group B consisted of 36 patients who had pulmonary arterial hypertension(pulmmonary artery mean pressure more...
Congenital Heart Disease in Neonatal Period and Infancy .
Jung Yun Choi, Hey Sun Lee
Clin Exp Pediatr. 1984;27(6):570-582.   Published online June 30, 1984
From July 1980 to June 1983, total 468 cases of infants of congenital heart disease were studied, who needed intensive care in infancy at Seoul National University Hospital. 1)Among 468 cases, 285 cases were diagnosed by cardiac catheterization or cardiac surgery and the other 183 cases by only clinical base. 2)Relative frequencies of these individual anomalies were in order of...


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