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Case Report
Two Cases of Successful Treatment with Atropine Sulfate in Persistent Vomiting beyond Pyloromyotomy of Infantile Hypertrophic Pyrolic Stenosis
Won Jung Kim, Min Jung Kim, Woo Jae Jo, Jae Young Kim, Sung Won Kim
Clin Exp Pediatr. 2000;43(5):704-709.   Published online May 15, 2000
Infantile hypertrophic pyloric stenosis(IHPS) is the most common condition requiring abdominal surgery in early infancy, and is caused by hypertrophied pyloric muscle. The development of successful surgical treatment in the early 1900s by Fredet and Ramstedt made it possible for infants worldwide to survive. Modern pediatric anesthetic techniques have virtually eliminated mortality from surgical management. Atropine sulfate is a cholinergic...
Original Article
Oscillometric Blood Pressure of Upper and Lower Extremities and Aortic Blood Flow Velocity in Neonates
Sang Young Bae, Hae Soon Kim, Se Jung Sohn, Young Mi Hong
Clin Exp Pediatr. 2000;43(4):484-488.   Published online April 15, 2000
Purpose : We studied the blood pressure difference between the upper and lower extremities in healthy newborn infants and the effect of isthmic narrowing of the aorta on making a possible difference. Methods : The blood pressure was measured with an oscillometric blood pressure device from four extremities of 62 healthy infants aged 1-15 days. A Doppler echocardiography was performed for...
Case Report
Five Cases of Prader-Willi or Angelman Syndrome Diagnosed by FISH in Neonate and Infancy
Hee Jung Chung, Young Rae Kim, Man Yong Han, Sook Hwan Lee
Clin Exp Pediatr. 2000;43(3):417-422.   Published online March 15, 2000
The Prader-Willi syndrome(PWS) and Angelman syndrome(AS) are clinically distinct syndromes with a shared cytogenetic deletion of chromosome 15q11q13 in most patients. Currently the diagnosis of PWS/AS is clinically suspected and can be confirmed by genetic laboratory tests. However, their diagnosis remains difficult in neonates and early infants because many features of the syndromes change with age and the typical features...
Original Article
Physiological Effects of Kangaroo Care(skin-to-skin care) in Small Preterm Infants and Their Parents
Heng-Mi Kim, Soo-Young Kim
Clin Exp Pediatr. 2000;43(3):365-371.   Published online March 15, 2000
Purpose : Kangaroo care is the practice of holding a small premaure infant, naked except for a diaper and hat, against a parent's chest. The purpose of this study is to determine the safety and feasibility of kangaroo care in a NICU as defined by physiological variables. Methods : Ten stable, spontaneously breathing preterm infants, weighing less than 2,000gm were...
The Seoul Infant Developmental Screening Test
Keun Lee
Clin Exp Pediatr. 2000;43(3):335-343.   Published online March 15, 2000
Purpose : The importance of early detection of developmental delays during infancy and preschool years has been repeatedly stressed, as early diagnosis of retardation increases the opportunities for effective therapy. Several screening tests developed in other countries are inappropriate for Korean children. The purpose of this study was to standardize a developmental screening method for Korean children. Methods : One hundred...
Effects of Cisapride on QTc Interval and QT Dispersion in Preterm Infants
Heui Seung Jo, Chang Won Choi, Yun Kyung Lee, Hee Seok Kim, Jun Dong Park, Jun Huh, Beyong Il Kim, Chung Il Noh, Jung-Hwan Choi
Clin Exp Pediatr. 2000;43(2):188-194.   Published online February 15, 2000
Purpose : Cisapride, a prokinetic agent, is widely used in preterm infants with feeding intolerance or gastroesophageal reflux. Although cisapride is regarded as a safe drug, increased QTc interval or ventricular arrhythmia has been reported in adults and neonates. So we prospectively examined the effects of cisapride on the QTc interval and QT dispersion in preterm infants. Methods : QTc interval...
A Study of Factors Affecting Time of First Stool in Premature Infants
Hyeong Doo Cho, Je Woo Kim, Young Ah Lee, Hae Sun Yoon
Clin Exp Pediatr. 1999;42(12):1645-1650.   Published online December 15, 1999
Purpose : To assess the effect of gestational age and illness severity, and the effect of antenatal exposure to magnesium sulfate, glucocorticoids, and antibiotics, on the timing of the first stool in preterm infants. Methods : Medical records of all preterm infants admitted to the neonatal ward at Kangnam Sacred Heart Hospital between March 1998 and August 1998 were reviewed. We...
Case Report
A Case of Infantile Marfan Syndrome
Sun Young Kim, Hee Ju Park
Clin Exp Pediatr. 1999;42(11):1583-1588.   Published online November 15, 1999
Marfan syndrome is infrequently diagnosed early in infancy. The morphologic characteristics and prognosis in infantile Marfan syndrome may be quite different from those in older patients. Characteristic cardiac findings in early life include mitral valve prolapse, valvular regurgitation, and aortic root dilation. Morbidity and mortality may be high for infants diagnosed with Marfan syndrome. Cardiac surgery for cardiovascular complication in...
A Case of Neonatal Myocardial Infarction with Structurally Normal Coronary Arteries
Ju Eun Lee, Seong Shik Park, Su Young Kim, Hee Ju Park
Clin Exp Pediatr. 1999;42(10):1459-1463.   Published online October 15, 1999
Original Article
A Comparative Study of Red Blood Cell Indices and Anemia by Feeding Patterns
Pill-Jin Shin, Chong-Woo Bae, Yong-Mook Choi
Clin Exp Pediatr. 1999;42(8):1104-1110.   Published online August 15, 1999
Purpose : Iron-deficiency anemia is the most common nutritional deficiency in young infants. This study was designed to determine feeding patterns in infants, and determine a correlation between feeding patterns and incidence of anemia. Methods : This study was conducted by taking blood tests (hemoglobin, hematocrit, and red cell indices) by venipuncture with the electronic counters from 221 infants aged 9-12...
Clinical Analysis and Comparison of Kawasaki Disease between Patients Younger than One Year of Age and Those over One Year of Age
Hee-Sun Chung, Kyung-Yil Lee, Ji-Whan Han, Sang-Won Cha, Dong-Joon Lee, Kyung-Tai Whang
Clin Exp Pediatr. 1999;42(7):936-942.   Published online July 15, 1999
Purpose : To identify the risk factors for coronary sequelae in Kawasaki disease, we analyzed and compared the clinical features and laboratory findings of Kawasaki disease in patients younger than one year of age with those over one year of age. Methods : A retrospective chart review was conducted of all children with Kawasaki disease who were admitted to the...
Doppler Echocardiographic Assessment of the Changes in Pulmonary Arterial Pressure in Preterm Infants with Respiratory Distress Syndrome
Sejung Sohn, Eun Ae Park
Clin Exp Pediatr. 1999;42(6):790-799.   Published online June 15, 1999
Purpose : The ratio of time to peak velocity(AT) and right ventricular ejection time(ET) as measured from the pulmonary artery Doppler waveform showed a close inverse correlation with pulmonary arterial pressure. The purpose of this study was to see the pattern of change in pulmonary arterial pressure assessed by AT/ET in preterm infants with respiratory distress syndrome (RDS). Methods : The...
Balloon Valvuloplasty of Pulmonary Stenosis in Patients Younger than 6 Months of Age
Yang Park, Do Jun Cho, Woo Sub Sim, In Seung Park, Eun Jung Bae, Seong Ho Kim
Clin Exp Pediatr. 1999;42(5):631-636.   Published online May 15, 1999
Purpose : Balloon valvuloplasty(BVP) is the treatment of choice for valvular pulmonary stenosis (PS). However, this procedure was usually performed in children older than 2 years. The purpose of the present study was to assess the safety and efficacy of BVP in young infants. Methods : Retrospective analysis of the medical records of 25 infants younger than 6 months of age...
Rehospitalization of Low-birth-weight Infants Who Were Discharged from NICU
Kyung Dan Choi, Young Suk Chae, Oh Kyung Lee
Clin Exp Pediatr. 1999;42(4):484-490.   Published online April 15, 1999
Purpose : We tried to compare normal term infants with low-birth-weight infants discharged from NICU by evaluating morbidity. So we studied rates of rehospitalization, reasons for rehospitalization and neonatal risk factors that affect rehospitalization of normal term infants and low-birth-weight infants discharged from NICU. Methods : This study was performed on 217 low-birth-weight infants discharged from NICU and 126 normal term...
A Clinical Study on Infantile Spasms with Vigabatrin Therapy
Seung Jung Oh, Sung Gun Park, Hyun Ho Kang, Sa Jun Chung
Clin Exp Pediatr. 1999;42(2):233-238.   Published online February 15, 1999
Purpose : Infantile spasms are considered an age-specific and malignant epilepsy. It is not controlled easily by general anticonvulsants. Therefore, this study aimed to assess vigabatrin(VGT) efficacy in infantile spasms. Methods : From January 1992 to December 1995, 35 children with infantile spasms, who were diagnosed at Kyung Hee University Hospital and treated vigabatrin, were analyzed retrospectively. Results : The ratio of...
Erratum
Reference Values of Hematologic and Biochemical Parameters of Nutrition around Weaning Period
Seung Joo Lee, Jeong Wan Seo, Jae Ock Park, Jae Hoon Shin, Hae Ran Lee, Ji Tae Chung, Hae Il Chung
Clin Exp Pediatr. 1999;42(1):6-14.   Published online January 15, 1999
Purpose : To determine the reference values of hematologic and biochemical parameters of nutrition around the weaning period. Methods : From February 1996 to March 1997, several nutritional laboratory values were evaluated in 130 healthy babies and 120 inpatients in the recovery stage of acute illness at six general hospitals. Results : Reference values in 9-month-old healthy babies(range : 6-12 months) were...
Original Article
Comparison of Treatment Course and Outcome between Medically and Surgically Treated Patent Ductus
Jeong Geun Kim, Jeong Nyun Kim, Dong Chul Park, Shin Yeong Lee, Hyun Chul Lee, Myung Jae Chey, Churl Young Chung,
Clin Exp Pediatr. 1998;41(10):1334-1341.   Published online October 15, 1998
Purpose : Early intervention is needed to treat patent ductus arteriosus(PDA) as it is a major cause of increased mortality in preterm infants. However, it is uncertain which is better, medical versus surgical management. We reviewed medical records to compare the treatment course and outcome between medically and surgically treated preterm PDA infants. Methods : Thirth-two Mechanically ventilated pretem infants(gestational age<34...
Thyroid Hormone Concentrations in Preterm Infants
Sung Keun Moon, Jeong Nyun Kim, Mi Jung Park, Myung Jae Choi, Chrul Young Chung
Clin Exp Pediatr. 1998;41(10):1324-1328.   Published online October 15, 1998
Purpose : To establish reference ranges for thyroid hormone concentrations in premature infants, we measured T4 and thyroid stimulating hormone(TSH) concentrations and analyzed the relation to gestational age and birth weight. Methods : Serum T4 and TSH concentrations were measured by radioimmunoassay for 391 premature infants born in Sanggye Paik Hospital for two years and eight months. Results : Gestational age of...
The Study of Transplacental Transfer of Immunoglobulin G in Premature Infants
Sung Soo Moon, Yoon Ki Kang, Soo Chul Cho, Jung Soo Kim
Clin Exp Pediatr. 1998;41(6):747-753.   Published online June 15, 1998
Purpose : Premature infants have low serum immunoglobulin G(IgG) levels because IgG is transplacentally acquired, primarily after 32-34 weeks of gestational age. We studied the transplacental transfer of serum IgG in preterm infants. Methods : The IgG levels in the sera were measured by radial immunodiffusion method(Behring nephelometer, Germany). Results : There was a significant difference between IgG concentration and gestational age; the IgG concentration increased...
Effects of Patent Ductus Arteriosus on Right Ventricle in Premature Infants : by M-mode and Doppler Echocardiography
Eun Jeung Kim, Eun Sil Lee, Young Hwan Lee, Son Moon Shin, Jeong Ok Hah
Clin Exp Pediatr. 1998;41(6):734-740.   Published online June 15, 1998
Purpose : Patent ductus arteriosus, derived left to right shunt flows, elevate the pulmonary artery pressure in infants and children and may alter right ventricular afterload thereby right ventricular function. Therefore, we examined the effects of patent ductus arteriosus on the right ventricular systolic time interval in premature infants by non-invasive Doppler echocardiography. Methods : Tweleve premature infants with patent ductus arteriosus were studied...
Atrial Ectopic Tachycardia in Infant
Myung Ja Yoon, Chung Il Noh
Clin Exp Pediatr. 1998;41(5):646-653.   Published online May 15, 1998
Purpose : Atrial ectopic tachycardia(AET) in older children and adult is characterized by being chronic, incessant and intractable. However, the nature of infantile AET is not defined yet. The purpose of this study was to evaluate our experience of infantile AET. Methods : We retrospectively reviewed the medical records of 13 infants(mean onset age, 2.8±2.3 months) diagnosed at Seoul National University...
Comparison of Continuous versus Intermittent Infusion of Indomethacin in PDA of Preterm Infants
Yun Kyoung Lee, Hee Seok Kim, Kyoung Ran Park, Chan Hu Park, June Dong Park, Beyong Il Kim, Woong Heum Kim, Jung Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1998;41(5):599-605.   Published online May 15, 1998
Purpose : Patent ductus arteriosus(PDA) of prematurity is very important disease to study because it causes many cases of perinatal morbidity and its incidence is now increasing. Nowadays indomethacin is the drug of choice for PDA closure, but its use has been limited due to its side effects. Therefore, we compared the effect and side effects of indomethacin according to...
A Clinical and Histological Study of Allergic Colitis in Infant
Jae Bok Kim, Kyung Mo Kim, Ki Soo Kim, Soo Young Pi, Yang Soon Park
Clin Exp Pediatr. 1998;41(4):521-528.   Published online April 15, 1998
Purpose : This study was done to evaluate the clinical and pathologic aspects of allergic colitis. Methods : This study evaluated 19 infants who presented with fresh blood mixed stools. Limited colonoscopy and biopsy were performed. Among the 19 infants, 13 infants were diagnosed as allergic colitis by histological findings. We analyzed the clinical and histological characteristics of 13 infants. Results : Male and female...
Comparison of Continuous Versus Intermittent Infusion of Indomethacin in PDA of Preterm Infants
Yun Kyoung Lee, Hee Seok Kim, Kyoung Ran Park, Chan Hu Park, June Dong Park, Beyong Il Kim, Woong Heum Kim, Jung Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1998;41(4):464-470.   Published online April 15, 1998
Purpose : Patent ductus arteriosus(PDA) of prematurity is very important disease to study because it causes many cases of perinatal morbidity and its incidence is now increasing. Nowadays indomethacin is the drug of choice for PDA closure, but its use has been limited due to its side effects. Therefore, we compared the effect and side effects of indomethacin according to the infusion method, continuous...
Case Report
A Case of Congenital Nephrotic Syndrome due to Diffuse Mesangial Sclerosis
Jung-Jin Yu, Dong Kyu Jin, Hae Il Cheong, Hyun Soon Lee, Yong Choi
Clin Exp Pediatr. 1998;41(3):415-419.   Published online March 15, 1998
Diffuse mesangial sclerosis(DMS) is one of the underlying pathology of congenital and infantile nephrotic syndrome. Infants with DMS develop nephrotic syndrome before 2 years of age and progress to end stage renal disease within 3 years of age. The authors experienced a case of isolated DMS in a 4-month-old male infant who had nephrotic syndrome for 1 month. The diagnosis...
Original Article
A Survey on the Attitudes toward Premature Infants
Oh Hyuk Kwon, Son Moon Shin
Clin Exp Pediatr. 1998;41(3):307-314.   Published online March 15, 1998
Purpose : We studied the attitudes of general population and medical personnels toward premature infants to establish basic data about prematurity. Methods : Ten students from Yeungnam University College of Medicine conducted field surveys on the general population at residential and commercial districts, and on medical personnels at private local clinics and hospitals in Taegu with a prepared questionaire from July...
Case Report
A Case of Genital Prolapse in Premature Baby
Woong Kyu Choi, Seung Cheol Lee, Yong Won Park, Chong Guk Lee, Sang Woo Kim
Clin Exp Pediatr. 1998;41(2):281-284.   Published online February 15, 1998
Neonatal genital prolapse is very rare and is usually associated with meningomyelocele or other anomalies of the central nervous system. Synonyms of genital prolapse are sacropubic hernia, pelvic relaxation, and pelvic organ prolapse. There are two types of genital prolapse including vaginal prolapse and uterovaginal prolapse. We experienced a case of uterovaginal prolapse in a 30 day-old premature infant, which...
Original Article
Postoperative Weight-Gain in Early Infants with Symptomatic Large Ventricular Septal Defect
Chang-Rang Kang, Hyang-Suk Yoon, Jong-Bum Choi, Soon-Ho Choi
Clin Exp Pediatr. 1997;40(12):1675-1680.   Published online December 15, 1997
Purpose : To investigate the postoperative patterns of weight-gain in early infants with ventricular septal defects(VSDs), we analyze 48 patients who received primary surgical closure of the symptomatic VSDs during 6 months of age in the period of 1993 through 1995. Methods : Forty-sixt infants met criteria for inclusion in the study. The mean follow up period was 14 months(3 to 36 months). Weight...
Influence of Phototherapy on Incidence of Patent Ductus Arteriosus in Very Low Birth W eight Infants
Hee Seok Kim, Ee Kyung Kim, Yun Kyoung Lee, Hee Eun Lee, Chan Hwu Park, Kyung Ran Park, Jun Dong Park, Beyong Il Kim, Woong Heum Kim, Jung-Hwan Choi, Yong Su Yun, Chong Ku Yun, Jeong Mi Lee
Clin Exp Pediatr. 1997;40(10):1410-1418.   Published online October 15, 1997
Purpose : Patent ductus arteriosus(PDA) is a common disease in very low birth weight infants(VLBWI). Hemodynamically significant PDA increases the morbidity and mortality of premature infants. Based on experimental model, light inhibits the constriction of immature piglet' s ductal rings. No specific mechanism adequately explains the effect of light on the relaxation of PDA. Several hypotheses, including activation of photosensitive metabolites, alterations in receptors, or...
Visual Evoked Potentials in Healthy Preterm Infants
Young Kook Kim, Young Hwan Kim, Young Sook Hong
Clin Exp Pediatr. 1997;40(9):1219-1226.   Published online September 15, 1997
Purpose : The visual evoked potentials(VEPs) offer a window both on visual system function and on cerebral or neurologic function. The study was performed to evaluate the maturation of VEP in preterm infants and to present a guide to detect high risk neonates who can develop neurodevelopmental abnormalities. Methods : The VEPs were recorded in response to binocular stimulus with light-emitting diode goggles. VEP recordings...
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