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Young Johang Kook 1 Article
Original Article
Treatment of diabetes insipidus with chlorpropamide
Kibok Kim, Kyu-Hae Chung, Yang Hyun Park, Kyung Woo Cho, Young Johang Kook
Clin Exp Pediatr. 1970;13(11):633-638.   Published online November 30, 1970
In two cases of diabetes insipidus (a five-year-old girl and a eight-year-old boy), oral administration of chlorpropamide in doses of 125~250 mg per day produced marked antidiuresis and concentration of urine. It was noted that the agent was effective also in the vasopressin-insensitive case (8-year-old boy). During the treatment endogenous creatinine clearance and the amount of sodium excreted, as well...
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