- Original Article
- Effects and adverse-effects of growth hormone therapy in
children with Prader-Willi syndrome: A two year study
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Su Jin Kim, Joong Bum Cho, Min Jung Kwak, Eun Kyung Kwon, Kyung Hoon Paik, Dong-Kyu Jin
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Clin Exp Pediatr. 2008;51(7):742-746. Published online July 15, 2008
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Purpose : The objective of this study was to evaluate the effects and adverse side-effects of growth hormone (GH) therapy in children with Prader-Willi syndrome (PWS).
Methods : Forty-one patients who had been treated with GH for more than two years (24 boys and 17 girls, mean age 7.3?.3 years during treatment initiation) were enrolled for this study.
Results : After... |
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- Clinical Characteristics and Genetic Analysis of
Prader-Willi Syndrome
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Ji Eun Lee, Kwang Bin Moon, Jong Hee Hwang, Eun Kyung Kwon, Sun Hee Kim, Jong Won Kim, Dong Kyu Jin
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Clin Exp Pediatr. 2002;45(9):1126-1133. Published online September 15, 2002
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Purpose : Prader-Willi syndrome(PWS) is a complex disorder affecting multisystems with characteristic clinical features. Its genetic basis is an expression defect in the paternally derived chromosome 15q11-q13. We analyzed the clinical features and genetic basis of PWS patients for early detection and treatment.
Methods : We retrospectively studied 24 patients with PWS in Department of Pediatrics, Samsung Medical Center, from... |
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