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Clinical Study of Mucocutaneous Lymph Node Syndrome-8 Cases.

Journal of the Korean Pediatric Society 1980;23(4):301-308.
Published online April 15, 1980.
Clinical Study of Mucocutaneous Lymph Node Syndrome-8 Cases.
Kee Young Yoon, Woo Gill Lee, Keun Soo Lee
Department of Pediatrics Hanyang University College of Medicine, Seoul, Korea.
急性 熱性 皮膚粘膜淋巴節症候群에 對한 臨床的 觀察
尹起英, 李愚吉, 李議洙
漢陽大學校 醫科大學 小兒科學敎室
Abstract
We observed clinically 8 cases of MCLS who were admitted to the Department of Pediatrics, Hanyang University Hospital from July, 1977 to August, 1979 and following results were obtained. 1. This syndrome developed in mainly under 2 years old of age with preponderence and in mainly summer season.2. Clinical manifestation of MCLS are: 1) fever lasting from one two weeks. 2) conjunctival injection. 3) changes in the mouth consisting of erythema of the mucosa, strawberry tongue? and dry reddened and fissuring lips. 4) indurative edema of hands and feet with erythema on palms and soles, followed by desquamation of the finger tips during convalescent stage. 5) erythematous rash, mainly in trunk. 6) unilateral cervical lymphadenopathy. 3. Lab. Findings are mild anemia, leukocytosis, increased ESR, positive CRP, increased 2-globulin, marked thrombocytosis during recovery stage, proteinuria, and pyuria. 4. Fever and other symptoms of MCLS were subsided in much shorter period(4-5days) in high dose of aspirin symptoms of aspirin group(150-185mg/kg/day) than in usual dose of aspirin group(7-8days). And so high dose aspirin therapy seems to be effective in the treatment of MCLS and definitely shortened the clinical course during acute stage. 5. In spite of high dose aspirin theray, no complication was noted and completely recovered in all cases without any complications.


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