| A Study on Serum Glucose, Insulin, and hGH Levels of Cord Blood in Newborn. |
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Cheol Won Park, Chang Soo Ra |
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Department of Pediatrics, College of Medicine, Chosun University, Kwang ju, Korea |
| 산모와 신생아제대혈의 혈청 Glucose 치,Insulin 치 및 hGH치에 관한 연구
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박철원, 나창수 |
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조선대학교 의과대학 소아과학교실 |
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| Abstract |
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We have studied the serum glucose, insulin and hGH levels of cord blood in newborn infants(38 cases) and the serum glucose, insulin and hGH levels of maternal blood at parturition (38 cases). For the purpose of analysis, the study objects were divided into two groups: normal infant group (32 cases) and premature infant group (6 cases). Serum glucose levels were measured by glucose oxidase method (V-Glucase, Nissui Set. Japan) and serum insulin levels were measured by the method of radioimmunoassay(Insulin RIA Kit, Japan) and serum hGH levels were measured by means of double antibody system of radioimmunoassay technique (hGH Kit, USA).
The following results were obtained. 1) The mean serum glucose levels of cord blood of the newborn infant were 71.99±16.40 mg/100ml and the mean serum glucose levels of maternal blood of the mother were 105.29
±15.79 mg/100 ml. In comparison of serum glucose levels for the newborn infants and mothers, the serum glucose levels of the newborn infants were significantly lower than those of the moths (p<0.01). In the newborn infants, the mean serum glucose levels of the normal infant group were 74.34±15.74 mg/100ml and the mean serum glucose levels of the premature infant group were 58.17±13.80 mg/100 ml. In comparison of serum glucose levels for the normal infant group and the premature infant group, the serum glucose levels of the normal infant group were significantly higher than those of the premature infant group (p<0.01). The correlation of the serum glucose levels of cord blood in the newborn infants and the serum glucose levels of the mothers were significant (r=0.772). 2)The mean serum insulin levels of cord blood of the newborn infants were 10.11±3.91 uU/ml and the mean serum insulin levels of maternal blood of the mother were 13.02±10. 55
uU/ml. In comparison of serum insulin levels for the new born infants and the mothers, the serum insulin levels of the newborn infants were those of the mothers but not significantly (P>0.05). In the newborn infants, the mean serum insulin‘ levels of the normal infant group were slightly higher than those of the premature infant group but not significantly. The correlation of the serum insulin levels of cord blood in the newborn infants and the serum insulin levels of the mothers were not significant (r=0.375). 3)The mean serum nGH levels of the cord blood of the newborn infants were 10.54±3. 96 ng/ml and the mean serum hGH levels of maternal blood of the mother were 1.83±1. 85 ng/ml. In comparison of serum hGH levels for the newborn infants and the mothers, the
serum hGH levels of the newborn infants were significantly higher than those of the mothers (p<0.01).
In the newborn infants, the mean serum hGH levels of the normal infant group were slightly higher than those of the premature infant group but not significantly. The correlation of the serum hGH levels of cord blood in the newborn; infants and the serum hGH levels of the mothers were not significant (r= -0.061). 4) The correlations between serum glucose and insulin levels, serum glucose and hGH levels, serum insulin and hGH levels of cord blood in the newborn infant were not significant. |
| Key Words:
Newborn infant, Glucose, Insulin, hGH |
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