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A Case of Transient Myeloproliferative Disorder in Down's Syndrome.

Journal of the Korean Pediatric Society 1990;33(2):252-258.
Published online February 28, 1990.
A Case of Transient Myeloproliferative Disorder in Down's Syndrome.
Ji Hye Kang1, Young Mi Hong1, Kyung Hee Kim1, Seung Joo Lee1, Ki Sook Hong2, Ok Kyung Kim2, Je Geun Chi3
1Department of Pediatrics, College of Medicine, Ewha Woman’s University, Seoul, Korea
2Department of Clinical Pathology, College of Medicine, Ewha Woman’s University, Seoul, Korea
3Department of Pathology, College of Medicine, Seoul Naitonal University, Seoul, Korea
Down 증후군 신생아에서의 일과성 골수증식장애 1례
강지혜1, 홍영미1, 김경희1, 이승주1, 홍기숙2, 김옥경2, 지제근3
1이화대학교 의과대학 소아과학교실
2이화대학교 의과대학 임상병리과학교실
3서울대학교 의과대학 병리과학교실
Received: 18 July 1989   • Accepted: 23 October 1989
Abstract
Transient myeloproliferative disorder has been reported in infant with Down's syndrome during neonatal period. This is clinically and hematologically indistinguishable from congenital acute leukemia. In contrast to congenital leukemia, complete clinical and hematological recovery occurs within weeks to months of diagnosis without antileukemic treatment. A neonate presented with jaundice, hepatosplenomegaly and mongoloid face was diagnosed as Transient myeloproliferative disorder. We report this case with a review of literature.
Key Words: Down’s Syndrome, Transient Myeloproliferative Disorder


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