Recent concepts on vitamin D in children and adolescents

Yang, Hye Ran; Seo, Jeong Wan; Kim, Yong Joo; Kim, Jae Young; Ryoo, Eell; Sim, Jae Geon; Yom, Hye Won; Chang, Ju Young; Jung, Ji A; Choi, Kwang Hae

Review Article

Korean Journal of Pediatrics 2009;52(10):1082-1089.
Published online October 15, 2009.

Recent concepts on vitamin D in children and adolescents

Hye Ran Yang¹, Jeong Wan Seo¹, Yong Joo Kim², Jae Young Kim³, Eell Ryoo⁴, Jae Geon Sim⁵, Hye Won Yom⁶, Ju Young Chang¹, Ji A Jung⁷, Kwang Hae Choi⁸

¹Committee on Nutrition; Korean Pediatric Society; Department of Pediatrics, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Seoul
²Committee on Nutrition, Korean Pediatric Society; Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea
³Committee on Nutrition, Korean Pediatric Society; Department of Pediatrics, Chungnam National University School of Medicine, Daejeon
⁴Committee on Nutrition, Korean Pediatric Society; Department of Pediatrics, Gachon University, Gil Hospital, Incheon
⁵Committee on Nutrition, Korean Pediatric Society; KSCH Pediatric Clinic, Chung-Ju, Korea
⁶Committee on Nutrition, Korean Pediatric Society; Departments of Pediatrics, Seoul Metropolitan Dong-bu Hospital, Seoul
⁷Committee on Nutrition, Korean Pediatric Society; Department of Nutritional Science, Maeil Daires Co., Ltd, Seoul
⁸Committee on Nutrition, Korean Pediatric Society; Department of Pediatrics, Youngnam University College of Medicine, Daegu, Korea

소아청소년기의 비타민 D에 대한 최신 지견

양혜란^¹^, 서정완^¹^, 김용주^²^, 김재영^³^, 류일^⁴^, 심재건^⁵^, 염혜원^⁶^, 장주영^¹^, 정지아^⁷^, 최광해^⁸

^¹대한소아과학회 영양위원회; 서울대학교 의과대학 분당서울대병원 소아과학교실
^²대한소아과학회 영양위원회; 한양대학교 의과대학 소아과학교실
^³대한소아과학회 영양위원회; 충남대학교 의과대학 소아과학교실
^⁴대한소아과학회 영양위원회; 가천의과대학 길병원 소아과학교실
^⁵대한소아과학회 영양위원회; 늘푸른 소아청소년과
^⁶대한소아과학회 영양위원회; 서울특별시 동부병원 소아청소년과
^⁷대한소아과학회 영양위원회; 매일유업(주) 영양과학연구실
^⁸대한소아과학회 영양위원회; 영남대학교 의과대학 소아과학교실

Correspondence:
Jeong Wan Seo, Email: jwseo@ewha.ac.kr

Abstract

Vitamin D is an important fat-soluble vitamin that functions as a prohormone and affects bone mineralization and calcium homeostasis. Vitamin D deficiency causesboth musculoskeletal manifestations, including rickets, and extra-musculoskeletal symptoms. Because vitamin D is naturally present in only some foods, intake of daily foods cannot meet the dietary reference intake for vitamin D. Sunlight is the main source of vitamin D in humans therefore, the lack of sunlight can easily cause vitamin D deficiency in children and adolescents. Vitamin D deficiency can be diagnosed on the basis ofits typical clinical manifestation, laboratory tests, and radiologic findings. Detection of vitamin D deficiency in children or adolescents necessitates the simultaneous administration of vitamin D and calcium supplements. To prevent vitamin D deficiency, 200 IU of daily vitamin D intake is recommended in infants, and 400 IU of daily vitamin D intake is recommended in Korean children and adolescents.

Key Words: Vitamin D, Rickets, Deficiency, Children, Adolescents