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A case of idiopathic pulmonary hemosiderosis with seasonal recurrence

Korean Journal of Pediatrics 2009;52(2):256-260.
Published online February 15, 2009.
A case of idiopathic pulmonary hemosiderosis with seasonal recurrence
Ga Young Kwak, Na Young Lee, Moon Hee Lee, Soo Young Lee, Seung Yun Chung, Jin Han Kang, Dae Chul Jeong
Department of Pediatrics, College of Medicine, The Catholic University of Korea
계절성으로 재발한 특발성 폐 혈철 침착증 1예
곽가영, 이나영, 이문희, 이수영, 정승연, 강진한, 정대철
가톨릭대학교 의과대학 소아과학교실
Correspondence: 
Dae Chul Jeong, Email: dcjeong@catholic.ac.kr
Abstract
Idiopathic pulmonary hemosiderosis (IPH) is a rare disease affecting mostly children. This disorder is characterized by recurrent episodes of hemoptysis, bilateral diffuse pulmonary infiltrates, and iron-deficiency anemia. An acute fulminant alveolar hemorrhage can be fatal due to respiratory failure, while chronic hemorrhage leads to hemosiderin-laden macrophages and pulmonary fibrosis. Genetic, autoimmune, allergic, environmental, and metabolic mechanisms of pathogenesis have been suggested, but the etiology of IPH remains unknown. We report on a 9-year-old girl with idiopathic pulmonary hemosiderosis who showed seasonal recurrences without cause.
Key Words: Idiopathic pulmonary hemosiderosis, Seasonal recurrence


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