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Clinical and Epidemiologic Study of Kawasaki Disease in Children 8 Years of Age and Older

Korean Journal of Pediatrics 2005;48(10):1139-1142.
Published online October 15, 2005.
Clinical and Epidemiologic Study of Kawasaki Disease in Children 8 Years of Age and Older
Yong Won Park1, Ji Whan Han2, In Sook Park3, Chang Hwi Kim4, Sung Ho Cha5, Jae Sook Ma6, Tae Chan Kwon7, Sang Bum Lee8, Chul Ho Kim1, Heung Jae Lee9, Yong Soo Yun10
1Department of Pediatrics, College of Medicine, Inje University, Seoul Paik Hospital, Seoul, Korea
2Department of Pediatrics, College of Medicine, Catholic University, Seoul, Korea
3Department of Pediatrics, College of Medicine, University of Ulsan, Korea
4Department of Pediatrics, College of Medicine, Soonchunhyang University, Buchun, Korea
5Department of Pediatrics, College of Medicine, Kyunghee University, Seoul, Korea
6Department of Pediatrics, College of Medicine, Chonnam National University, Kwangju, Korea
7Department of Pediatrics, College of Medicine, Keimyung University, Daegu, Korea
8Department of Pediatrics, College of Medicine, Kyungpook National University, Daegu, Korea
9Department of Pediatrics, College of Medicine, Sungkyunkwan University, Seoul, Korea
10Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea
8세 이상 소아에서의 가와사끼병의 임상 역학적 연구
박용원1, 한지환2, 박인숙3, 김창휘4, 차성호5, 마재숙6, 권태찬7, 이상범8, 김철호1, 이흥재9, 윤용수10
1인제대학교 의과대학 소아과학교실
2가톨릭대학교 의과대학 소아과학교실
3울산대학교 의과대학 소아과학교실
4순천향대학교 의과대학 소아과학교실
5경희대학교 의과대학 소아과학교실
6전남대학교 의과대학 소아과학교실
7계명대학교 의과대학 소아과학교실
8경북대학교 의과대학 소아과학교실
9성균관대학교 의과대학 소아과학교실
10서울대학교 의과대학 소아과학교실
Correspondence: 
Yong Won Park, Email: yongpw@hanmail.net
Abstract
Purpose
: The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease(KD) in children 8 years of age and older.
Methods
: For the epidemiologic study of KD in Korea, data of total 15,692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of 211 KD patients 8 years of age and older were analyzed and compared with those of the KD patients less than 8 years of age.
Results
: 211 patients 8 years of age and older(1.3% of total KD patients) with the mean age of 9.8 years, included 142 cases aged 8-10 years, 42 cases aged 10-12 years, and 27 cases aged 12 years and older. The male-to-female ratio was 1.9 : 1, the recurrence rate was 3.8%, and the prevalence of cases in sibling was zero. Coronary arterial(CA) abnormalities were detected by echocardiography in 25.4% of the cases, including 7.6% of CA aneurysm cases. There was 1 case complicated by myocardial infarction.
Conclusion
: Comparing with the data of the KD patients less than 8 years of age, data of 211 patients 8 years of age and older showed significantly higher incidences of CA abnormalities(25.4% : 19.8%) and CA aneurysms(7.6% : 4.0%).
Key Words: Kawasaki disease , Mucocutaneous lymph node syndrome , Coronary aneurysm , Epidemiology , Child


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