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Medical Treatment of Infantile Hypertrophic Pyloric Stenosis Using Intravenous Atropine Sulfate

Journal of the Korean Pediatric Society 1999;42(6):874-878.
Published online June 15, 1999.
Medical Treatment of Infantile Hypertrophic Pyloric Stenosis Using Intravenous Atropine Sulfate
Kun Hee Lim1, Son Moon Shin1, Han Ku Moon1, Mi Soo Hwang2
1Departments of Pediatrics, College of Medicine, Yeungnam University, Taegu, Korea.
2Departments of Radiology, College of Medicine, Yeungnam University, Taegu, Korea.
영아 비후성 유문 협착증에 대한 아트로핀 치험 1례
임근희1, 신손문1, 문한구1, 황미수2
1영남대학교 의과대학 소아과학교실
2영남대학교 의과대학 진단방사선과학교실
Correspondence: 
Son Moon Shin, Email: smshin@medical.yeungnam.ac.kr
Abstract
Infantile hypertrophic pyloric stenosis(IHPS) is one of the most common causes of nonbilious vomiting in early infancy, and is caused by hypertrophied pyloric muscle but its exact etiology and pathogenesis are still unknown. Fredet-Ramstedt pyloromyotomy has been accepted as the treatment of choice for IHPS. Atropine is a cholinergic blocking agent with potent antimuscarinic activity that decreases peristaltic contractions by relaxing smooth muscles. We treated a case of IHPS in a 33-day-old male infant by administering atropine sulfate intravenously. One day after atropine sulfate administration, he did not vomit any more. Ultrasonograms of the pyloric canal which were done on eight days and three weeks after atropine treatment revealed no limitation in the passage of gastric content, and no changes in the muscle thickness and length of the pyloric canal. Thereafter, he did not show up at follow ups, we received his mother's answer through phone that he did not suffer from vomiting and he was growing well at 5 months of age.
Key Words: Idiopathic hypertrophic pyloric stenosis, Atropine sulfate


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