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Clinical Study of Aseptic Meningitis from 1996 to 1998 in Chounju Presbyterian Medical Center, Korea

Journal of the Korean Pediatric Society 1999;42(6):765-770.
Published online June 15, 1999.
Clinical Study of Aseptic Meningitis from 1996 to 1998 in Chounju Presbyterian Medical Center, Korea
Seung Woo Paik, Byoung Lae O, Sun Ja Cho, Young Taek Chang
Department of Pediatrics, Presbyterian Medical Center, Chounju, Korea.
1996년도에서 1998년까지 전주 예수병원에서 입원 치료받은 무균성 뇌막염의 임상적 고찰
백승우, 오병래, 조선자, 장영택
전주예수병원 소아과
Correspondence: 
Seung Woo Paik, Email: 1
Abstract
Purpose
: There was an explosive prevalence of aseptic meningitis for three years from 1996 to 1998. In this study, we reported the time of outbreak, clinical manifestation, CSF examination of patient, and CSF virus culture.
Methods
: We reviewed clinical records of 794 aseptic meningitis patient who had been admitted to Chounju Presbyterian Medical Center. The total number of patients was 794 patients from 1996 to 1998.
Results
: The ratio of male to female was 1.74 : 1. Aseptic meningitis was prevalent in summer and fall. The majority of aseptic meningitis occurred in children between 1 and 5 years of age. The frequency of clinical manifestations was fever, vomiting, headache, and abdominal pain. In peripheral blood examination, leukocytosis(WBC>10,000/mm3) was showed in 67.1% of cases. On CSF examination, WBC count were less than 500/mm3 in 87.4% of case and protein levels were less than 60mg/dl in 91.9% of case and glucose levels were more than 40 mg/dl in 97.9% of case. In CSF virus culture, type nonspecific Enterovirus, Echovirus 9, Echovirus 4, Echovirus 6 was cultured.
Conclusion
: There were an epidemic of aseptic meningitis in the Chounju area from July to September in 1996 and from April to June in 1997 and 1998. As for clinical manifestations, CSF examination of aseptic meningitis patients showed no great difference compared to other aseptic meningitis study. Causative organisms were type nonspecific Enterovirus, Echovirus 9, Echovirus 4, Echovirus 6 and were cultured.
Key Words: Aseptic meningitis


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