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A Case of Multiple Sclerosis

Journal of the Korean Pediatric Society 1998;41(2):264-269.
Published online February 15, 1998.
A Case of Multiple Sclerosis
Young Hee Ha, Jong Hyun Kim, Soo Joong Lee, Dae Kyun Koh
Department of Pediatrics, Catholic University, College of Medicine, Seoul, Korea
다발성 경화증(Multiple Sclerosis) 1예
하영희, 김종현, 이수중, 고대균
가톨릭대학교 의과대학 소아과학교실
Correspondence: 
Young Hee Ha, Email: 1
Abstract
Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system and its lesions are multiple in time as well as space. We experienced a case of a 14-year-old-girl with dysphagia, paresthesia and headache. Brain MRI scans demonstrated high signal intensities on T2-weighted images at the medulla and upper cervical cord. Acute disseminated encephalomyelitis was diagnosed and methylprednisolone pulse therapy was done. After 6 months she re-experienced diplopia, ophthalmoplegia and other neurological symptoms. There were increased signal intensities on T2-weighted image at the tegmentum, periaqueduct and hypothalamus in follow-up brain MRI. Finally, a diagnosis of multiple sclerosis was made. Methylprednisolone pulse therapy was started and she then recovered without any neurologic symptoms and signs. We report a case of multiple sclerosis in a 14-year- old-girl who was confirmed by clinical courses and serial MRIs.
Key Words: Multiple sclerosis, Acute disseminated encephalomyelitis, Brain MRI


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