- Review Articles
- General Pediatrics
- Apparent life-threatening event in infancy
- Hee Joung Choi, Yeo Hyang Kim
- Clin Exp Pediatr. 2016;59(9):347-354. Published online September 21, 2016
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An apparent life-threatening event (ALTE) is defined as the combination of clinical presentations such as apnea, marked change in skin and muscle tone, gagging, or choking. It is a frightening event, and it predominantly occurs during infancy at a mean age of 1–3 months. The causes of ALTE are categorized into problems that are: gastrointestinal (50%), neurological (30%), respiratory (20%),...
- Endocrinology
- Effects of early menarche on physical and psychosocial health problems in adolescent girls and adult women
- Jae-Ho Yoo
- Clin Exp Pediatr. 2016;59(9):355-361. Published online September 21, 2016
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The menarcheal age of Korean women has been rapidly decreasing for the last 50 years, and the average menarcheal age of women born in the 1990s is approaching 12.6 years. In addition, interest in early puberty has been increasing recently owing to the rapid increase in precocious puberty. Generally, out of concern for short stature and early menarche, idiopathic central...
- Original Articles
- Gastroenterology
- Clinical significance of serum alanine aminotransferase and lifestyle intervention in children with nonalcoholic fatty liver disease
- Kyoung Ah Kwon, Peter Chun, Jae Hong Park
- Clin Exp Pediatr. 2016;59(9):362-367. Published online September 21, 2016
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Purpose This study aimed to investigate the clinical significance of serum alanine aminotransferase (ALT) levels in children with nonalcoholic fatty liver disease (NAFLD) and the effect of lifestyle intervention on NAFLD.
Methods The clinical data of 86 children diagnosed with NAFLD were reviewed retrospectively. Forty-six patients belonged to the elevated ALT group and 40 to the normal ALT group. The clinical parameters of...
- Risk factors of delayed diagnosis of acute appendicitis in children: for early detection of acute appendicitis
- Jea Yeon Choi, Eell Ryoo, Jeong Hyun Jo, Tchah Hann, Seong Min Kim
- Clin Exp Pediatr. 2016;59(9):368-373. Published online September 21, 2016
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Purpose This study examined the risk factors of a delayed diagnosis of acute appendicitis in children undergoing an appendectomy.
Methods This retrospective study involved children aged below 18 years, who underwent an appendectomy. After dividing them into a delayed diagnosis group and nondelayed diagnosis group according to the time interval between the initial hospital visit and final diagnosis, the risk factors of delayed...
- Oncology
- Metformin displays
in vitro andin vivo antitumor effect against osteosarcoma - Yunmi Ko, Aery Choi, Minyoung Lee, Jun Ah Lee
- Clin Exp Pediatr. 2016;59(9):374-380. Published online September 21, 2016
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Purpose Patients with unresectable, relapsed, or refractory osteosarcoma need a novel therapeutic agent. Metformin is a biguanide derivative used in the treatment of type II diabetes, and is recently gaining attention in cancer research.
Methods We evaluated the effect of metformin against human osteosarcoma. Four osteosarcoma cell lines (KHOS/NP, HOS, MG-63, U-2 OS) were treated with metformin and cell proliferation was evaluated using...
- Case Report
- Neurology
- Painful legs and moving toes syndrome in a 16-year-old girl
- Seung Soo Kim, Yong Seung Hwang, Young Chang Kim
- Clin Exp Pediatr. 2016;59(9):381-383. Published online September 21, 2016
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Painful legs and moving toes (PLMT) syndrome is characterized by spontaneous movements of the digits and pain in one or both lower extremities. Of the reported cases, a majority of the patients was female, and the mean age of onset was 58 years. Only one pediatric case has been reported so far. Herein, we report the first adolescent case of...
- Erratums
- Cardiology
- Erratum: Pulmonary stenosis and pulmonary regurgitation: both ends of the spectrum in residual hemodynamic impairment after tetralogy of Fallot repair
- Byung Won Yoo, Han Ki Park
- Clin Exp Pediatr. 2016;59(9):384-385. Published online September 21, 2016
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- Neurology
- Erratum: Developmental profiles of preschool children with delayed language development
- Ji Eun Jeong, Hyung Jik Lee, Jin Kyung Kim
- Clin Exp Pediatr. 2016;59(9):386-386. Published online September 21, 2016
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- Infection
- Erratum:
Pneumocystis jirovecii pneumonia in pediatric patients: an analysis of 15 confirmed consecutive cases during 14 years - Kyung-Ran Kim, Jong Min Kim, Ji-Man Kang, Yae-Jean Kim
- Clin Exp Pediatr. 2016;59(9):387-387. Published online September 21, 2016
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