Article 58(3); Mar 2015
Review Articles
Nutritional strategy of early amino acid administration in very low birth weight infants
Byong Sop Lee
Clin Exp Pediatr. 2015;58(3):77-83.   Published online March 20, 2015

Relative to a fetus of the same gestational age, very low birth weight (VLBW) infants are more likely to be underfed and to undergo growth restriction during their early hospital stay. The current trend towards "early and aggressive" nutritional strategies in VLBW infants aims to overcome the early nutritional deficiency and thereby boost postnatal catch-up growth, simultaneously improving long-term neurodevelopmental...

Update of genetic susceptibility in patients with Kawasaki disease
Kyung Lim Yoon
Clin Exp Pediatr. 2015;58(3):84-88.   Published online March 20, 2015

Kawasaki disease (KD) is an acute systemic vasculitis that predominantly affects children, and can result in coronary artery lesions (CAL). A patient with KD who is resistant to treatment with intravenous immunoglobulin (IVIG) has a higher risk of developing CAL. Incomplete KD has increased in prevalence in recent years, and is another risk factor for the development of CAL. Although...

Original Articles
House dust mite-specific immunoglobulin E and longitudinal exhaled nitric oxide measurements in children with atopic asthma
Youn Kyung Lee, Sohyoung Yang, Joohyun Park, Heon Kim, Youn-Soo Hahn
Clin Exp Pediatr. 2015;58(3):89-95.   Published online March 20, 2015
Purpose

House dust mite (HDM) has been suggested to be the most important aeroallergen responsible for atopic asthma in Korea. We aimed to investigate that specific IgE antibodies to HDM and other common indoor aeroallergens contribute differently to total serum IgE and show different relationships with longitudinal fractional exhaled nitric oxide (FeNO) measurements in Korean atopic asthmatic patients.

Methods

A total of 193...

Relationship between serum 25-hydroxyvitamin D and interleukin-31 levels, and the severity of atopic dermatitis in children
Bo Ram Cheon, Jeong Eun Shin, Yun Ji Kim, Jae Won Shim, Deok Soo Kim, Hye Lim Jung, Moon Soo Park, Jung Yeon Shim
Clin Exp Pediatr. 2015;58(3):96-101.   Published online March 20, 2015
Purpose

Atopic dermatitis (AD) is a chronic inflammatory relapsing skin disorder. Vitamin D plays a pivotal role in the development of AD, and interleukin (IL) 31 is known to be related to pruritus in AD. The aim of our study was to determine whether 25-hydroxyvitamin D (25(OH)D) levels are related to IL-31 levels or to the severity of AD.

Methods

We enrolled 91...

Prevalence of human parechovirus and enterovirus in cerebrospinal fluid samples in children in Jinju, Korea
Ji-Hyun Seo, Jung Sook Yeom, Hee-Shang Youn, Tae-Hee Han, Ju-Young Chung
Clin Exp Pediatr. 2015;58(3):102-107.   Published online March 20, 2015
Purpose

Human parechovirus (HPeV) and enterovirus (EV) are causative agents of a sepsis-like illness in neonates and of infections of the central nervous system in young children. The objectives of this study were to assess the prevalence of HPeV3 and EV infection in young children with a sepsis-like illness or with meningitis in Jinju, Korea.

Methods

Cerebrospinal fluid (CSF) samples were collected from...

Case Reports
DiGeorge syndrome who developed lymphoproliferative mediastinal mass
Kyu Yeun Kim, Ji Ae Hur, Ki Hwan Kim, Yoon Jin Cha, Mi Jung Lee, Dong Soo Kim
Clin Exp Pediatr. 2015;58(3):108-111.   Published online March 20, 2015

DiGeorge syndrome is an immunodeficient disease associated with abnormal development of 3rd and 4th pharyngeal pouches. As a hemizygous deletion of chromosome 22q11.2 occurs, various clinical phenotypes are shown with a broad spectrum. Conotruncal cardiac anomalies, hypoplastic thymus, and hypocalcemia are the classic triad of DiGeorge syndrome. As this syndrome is characterized by hypoplastic or aplastic thymus, there are missing...

Massive pulmonary hemorrhage in enterovirus 71-infected hand, foot, and mouth disease
Dong Seong Lee, Young Il Lee, Jeong Bae Ahn, Mi Jin Kim, Jae Hyun Kim, Nam Hee Kim, Jong Hee Hwang, Dong Wook Kim, Chong Guk Lee, Tae Won Song
Clin Exp Pediatr. 2015;58(3):112-115.   Published online March 20, 2015

Hand, foot, and mouth disease (HFMD) is an acute, mostly self-limiting infection. Patients usually recover without any sequelae. However, a few cases are life threatening, especially those caused by enterovirus 71 (EV71). A 12-month-old boy was admitted to a primary hospital with high fever and vesicular lesions of the mouth, hands, and feet. After 3 days, he experienced 3 seizure...

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