Clinical and Experimental Pediatrics

Review Articles

Infection

Safety monitoring of COVID-19 vaccines: February 26, 2021, To June 4, 2022, Republic of Korea

Yeon-Kyeng Lee, Yunhyung Kwon, Yesul Heo, Eun Kyoung Kim, Seung Yun Kim, Hoon Cho, Seontae Kim, Mijeong Ko, Dosang Lim, Soon-Young Seo, Enhi Cho

Clin Exp Pediatr. 2023;66(10):415-423. Published online June 13, 2023

· Enhanced safety monitoring system of coronavirus disease 2019 (COVID-19) vaccines were implemented to detect signals rapidly as part of the national COVID-19 vaccination program.
· As of June 4, 2023, reported adverse events after COVID-19 vaccination was 0.38% among 125,107,883 doses of COVID- 19 vaccines administered.
· Most reported adverse reactions after COVID-19 vaccinations have shown nonserious and mild intensity.

DOI: https://doi.org/10.3345/cep.2022.00815

Nephrology (Genitourinary)

Kidney complications associated with COVID-19 infection and vaccination in children and adolescents: a brief review

Hee Sun Baek, Min Hyun Cho

Clin Exp Pediatr. 2023;66(10):424-431. Published online June 28, 2023

Web of Science 2 Crossref 2

Several observational studies have shown that acute kidney injury affects up to 46% of children and adolescents who develop severe postinflammatory responses, such as multisystem inflammatory syndrome in childhood, due to coronavirus disease 2019 (COVID-19). Although causality has not been established, some cases of glomerulopathy or nephrotic syndrome occurring after COVID-19 infection or vaccination have been reported. Therefore, kidney complications associated with these conditions in children and adolescents warrant attention.

DOI: https://doi.org/10.3345/cep.2023.00738

Immunology

Systemic autoinflammatory disorders

Dae Chul Jeong

Clin Exp Pediatr. 2023;66(10):432-438. Published online June 14, 2023

Web of Science 1 Crossref 1

· Systemic autoinflammatory disorders (SAID) are disorders caused by dysregulation of the innate immunity with genetic background, leading to recurrent episodes of systemic inflammation.
· SAID is characterized by recurrent acute inflammatory responses including fever or skin manifestations, unrelated with infection or malignancy.
· Diagnosis is based on family and long-term history with detailed clinical and laboratory manifestations during febrile periods.

DOI: https://doi.org/10.3345/cep.2022.01186

Editorial

Immunology

Systemic autoinflammatory disorders: autoinflammatory and autoimmune disorders

Young Dae Kim

Clin Exp Pediatr. 2023;66(10):439-440. Published online July 4, 2023

Web of Science 1 Crossref 1

· Systemic autoinflammatory disorders (SAIDs) typically have an early onset in life, and may have close relatives may have similar disease.
· SAIDs should be suspected in any patient, especially children, who experience persistent or recurrent inflammatory episodes that fail to fit the pattern of other established diseases.
· Advancements in the understanding of autoinflammation will provide novel diagnostic and therapeutic options for SAIDs patients.

DOI: https://doi.org/10.3345/cep.2023.00605

Original Articles

Developmental and Behavioral Medicine

Neonatal risk factors associated with attention-deficit/hyperactivity disorder: an umbrella review

Ensiyeh Jenabi, Erfan Ayubi, Sajjad Farashi, Saeid Bashirian, Fereshteh Mehri

Clin Exp Pediatr. 2023;66(10):441-446. Published online July 14, 2023

Web of Science 1 Crossref 1

Question: The risk factors for attention deficit hyperactivity disorder (ADHD), such as breastfeeding, congenital heart disease, and low birth weight, in neonates are not well understood.
Finding: This umbrella review obtained significant effect sizes for ADHD for congenital heart disease (odds ratio [OR], 3.04), low birth weight (OR, 2.25), never breastfed (OR, 1.55), and Apgar score (OR, 1.30).
Meaning: Congenital heart disease, low birth weight, lack of breastfeeding, and Apgar scores were significant factors for ADHD.

DOI: https://doi.org/10.3345/cep.2022.01396

Impact of short and intensive art-based intervention on symptomatology and social interactions among children with autism spectrum disorder

Deldar Morad Abdulah, Bayar Mohammed Omar Abdulla, Pranee Liamputtong

Clin Exp Pediatr. 2023;66(10):447-454. Published online September 14, 2023

Question: Does a short and intensive art-based intervention affect symptoms and social interactions among children with autism spectrum disorder (ASD)?
Finding: The short and intensive art-based intervention did not affect symptoms in children with ASD level 2 or 3, including social awareness, social cognition, social communication, social motivation, and autistic mannerisms.
Meaning: The short and intensive art-based intervention did not improve the symptoms of patients with ASD.

DOI: https://doi.org/10.3345/cep.2023.00640

Letter to the Editor

Allergy

Increased serum eosinophilic cationic protein in children with nonspecific chronic cough

Young Hwan Kim, Yoon Young Jang, Jieun Jeong, Hai Lee Chung

Clin Exp Pediatr. 2023;66(10):455-457. Published online September 14, 2023

DOI: https://doi.org/10.3345/cep.2023.00416

Cited By 22	Retinopathy of prematurity: a review of epidemiology and current treatment strategies
Cited By 20	Genetic factors in precocious puberty
Cited By 18	Global relationship between parent and child obesity: a systematic review and meta-analysis
Cited By 14	Gross motor dysfunction and balance impairments in children and adolescents with Down syndrome: a systematic review
Cited By 13	Etiological and pathophysiological enigmas of severe coronavirus disease 2019, multisystem inflammatory syndrome in children, and Kawasaki disease

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