Question: What are the parental needs and challenges when their children return to school after cancer? Finding: In addition to scholastic aptitude-oriented programs, emotional and psychosocial support is necessary for a successful return to school. Meaning: Pediatric oncologists should actively engage in improving oncology practices to better integrate individualized school plans and educate peers and teachers to improve health literacy to make them understand the needs of children with cancer. |
Kikuchi-Fujimoto disease (KFD) is a benign disease, which is characterized by a cervical lymphadenopathy with fever, and it often mimics malignant lymphoma (ML). 2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) is a powerful imaging modality for the diagnosis, staging and monitoring of ML, with the limitations including the nonspecific FDG uptake in infectious or inflammatory processes. This study compared clinical... |
Natural history and consequences of the novel 2009 influenza A H1N1 (2009 H1N1) infection in immunocompromised pediatric patients are not yet fully understood. In this study, we investigated the clinical features and outcomes of the 2009 H1N1 infection in pediatric patients with hematological and oncological diseases. We retrospectively reviewed the medical records of 528 patients who had hematological and oncological diseases... |
Neuroblastoma is one of the most common extracranial solid tumor of childhood, and treatment of refractory neuroblastoma remains a significant clinical problem. Iodine-131-metaiodobenzylguanidine (131I-MIBG) therapy is an alternative approach to treat stage Ⅳ neuroblastoma. We report the palliative effect of 131I-MIBG in three cases of relapsed neuroblastoma after autologous peripheral blood stem cell transplantation. 131I-MIBG is an effective and relatively... |
Purpose : Neutropenic enterocolitis is an acute, life-threatening inflammation of the small and large bowel, often seen in children with malignancies during periods of prolonged or severe neutropenia. The optimal management for typhlitis in pediatric oncology patients has been debateful between operative and nonoperative approaches. The purpose of this study was to review the outcome of medical management of patients... |
Purpose : Radiotherapy is effective in local treatment for retinoblastoma. However, asymmetric facial hypoplasia after radiation is a serious late effect. This study was performed to investigate the effects of enucleation and chemotherapy with or without radiotherapy in advanced intraocular and intraorbital retinoblastoma. Methods : Between 1985 October and 2006 December, the records of thirty five patients who were diagnosed as... |
Purpose : The anthracyclines (AC) are widely used chemotherapeutic agents for pediatric cancers. However, the therapeutic use of these agents is limited by their cardiotoxicity. The aim of the present study was to investigate the usefulness of plasma B-type natriuretic peptide (BNP) levels as a marker for AC-induced cardiotoxicity compared to echocardiography in Korean children with cancer. Methods : Fifty-five pediatric... |
To understand the hemolytic anemia (HA) in children, the diagnostic approach and management of hereditary and acquired HA are described. The hereditary hemolytic anemia (HHA) can be classified according to the pathogenesis into three types : RBC membrane defects, hemoglobinopathies, and RBC enzymopathies. Clinical characteristics, laboratory findings and molecular defects of these three types are presented briefly. In Korea,... |
Purpose : Anemia is still the most common nutrient deficiency worldwide, especially in adolescence because of an insufficient supply of iron, an increased iron requirement due to accelerated physical growth and blood loss due to menstruation in girls. This study was designed to assess the anemia and serum iron status of middle school girls. Methods : Hematologic examinations, physical examinations and... |
Purpose : Patent ductus arteriosus, derived left to right shunt flows, elevate the pulmonary artery pressure in infants and children and may alter right ventricular afterload thereby right ventricular function. Therefore, we examined the effects of patent ductus arteriosus on the right ventricular systolic time interval in premature infants by non-invasive Doppler echocardiography. Methods : Tweleve premature infants with patent ductus arteriosus were studied... |
Purpose : Pain inflicted by diagnostic or therapeutic procefures is a major source of concern for young patients, their families, and the medical staff. Needle puncture may be painful, is often unpleasant and occasionally can cause considerable distress. Studies on eutectic combinations of two anesthetic drugs are rare. In this article, we evaluate the efficacy of a new topical anesthetic... |
This study was conducted to investigate the safety of the umbilical venous blood for antologous transfusion in the premature newborn babies. Umbilical venous blood was collected with aseptic technique immediately after delivery from 270 healthy mothers admitted to the Yeungnam University Hospital between March 1, 1992 and August 31, 1992. The volume of the blood and the time taken for... |
This study was conducted to evaluate the effect of prolonged treatment in children with chronic hepatitis B will combination of alpha-interferon and acyclovir. The study population consisited of & patients with chronic hepatitis B who showed histological findings compatible with chronic active hepatitis (4 cases) or chronic persistent hepatitis (3 cases) on liver biopsy and had elevated AST and ALT with... |
This study was conducted to investigate plasma levels of oral methotrexate in rabbits and children receiving maintenance chemotherapy for acute lymphocytic leukemia. Eight New Zealand white rabbits, weighing 2kg in body weight, were divided into 3 groups and 5mg of methotrexate from 3 different manufactorying company was administered to the each group rabbits via nasogastric tube. Time to peak concentration ranged from... |
This study was conducted to investigate the effects of CNS prophylaxis with 1800 cGy cranial irradiation and intrathecal methotrexate (MTX) chemotherapy on intellectual function of the chil- dren with acute lymphocytic leukemia (ALL). Thirteen longterm survivors with ALL who were treated with 1800 cGy cranial irradiation and intrathecal MTX for CNS prophylaxis at pediatric department of Yeungnam University Hospital from May, 1983 to November, 1988... |
To develop more reliable screening test for ABO incompatible hemolytic disease than commonly employed and to identify possible indicators of severity of hyperbilirubinemia, a pilot study was performed by measuring the carboxyhemoglobin (HbCO) of the newborn babies within 48 hours after birth. Forty eight newborn babies were studied and carboxyhemoglobin was measured by spectro- photometry and serum bilirubin was measured by Diazo coupling method. There... |
This study was conducted to investigate the prevalence rate of anemia and iron deficiency in pubertal girls in urban and rural areas. Venous peripheral blood was sampled from 346 girls who were randomly selected from 1,900 students of one girls’ middle school in Taegu city and all of 311 girls attending two middle schools in rural area, one in Cheungdo county and, another... |
In order to confirm the effect of unilateral pneumonectomy on the compensatory growing pattern and the function of the type II pneumocyte in the contralateral lung, pneumonectomy was performed on the right lung of the New Zealand White rabbits. Five days after the surgery, pneumonectomized (PN) and control(CN) rabbits* lung were resected. As a result f the measurement of the left lung weight and... |
In eight cases of diabetes insipidus who were diagnosed at the pediatric department of Yeungnam University Hospital from July 1985 till May 1986, the levels of plaana AVP were measured by radioimmunoassay and the effects of various treatment were studied. In central diabetes insipidus patients basal plasma AVP level was 2.92 ±2.55 pg/ml which was significantly lower than the level of control group, 8.25... |
We experienced a case of Hallermann-Streiff syndrome in a 3 month old male with hepatitis B characterized by dyscephaly with bird face, proportionate nanism, hypotrichosis, atrophy of skin, bilateral microphthalmia and congenital cataract. A brief review of literature was made. |
A clinical trial for the therapeutic effect of heparin on DIC was conducted on 22 patients of DIC who were admitted to the pediatric department of Yeungnam University Hospital from September 1, 1984 to May 31, 1986. In addition to the conservative treatment, intensive care of underlying disease and specific replacement therapy for DIC, heparin was administered to the one-half of the patients... |
For the determination of the sensitivity and specificity of pulsed Doppler echocardiographic (PDE) diagnosis of patent ductus arteriosus (PDA), we evaluated 108 children with congenital heart disease by suprasternal and parasternal approaches. PDA was diagnosed when continuous turbulent flow(CTF) or PDA jet flow was recorded in main pulmonary artery (MPA) by parasternal approach and when reverse diastolic flow(RDF) was detected in descending aorta and no... |
Liver size was measured in 100 healthy newborn infants of gestational ages 38 to 42 weeks who were born at the Yeungnam University Hospital. The liver span was determined by measuring the distance between the percussed upper and palpated lower liver borders along the mid clavicular line (P-P method). The mean liver span was 4.6±0.3 cm. Liver span measured by... |
A case of Incontinentia pigmenti, Bloch-Sulzberger type, is presented with the review of related literatures. One month old female infant was admitted with irregular, grouped vesicobullous lesion on the whole body especially on the trunk and extremities which have been persistent since birth. No familial traits were noted. Diagnosis was made by the characteristic clinical and laboratory and histopathologic:findings |