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Original Article
The relationship between Gly71Arg and TATA box polymorphism of UGT1A1 gene and prolonged hyperbilirubinemia of breast milk feeding infant in Korean
Jae Myoung Lee, Young Ji Han, Ji Sook Kim, Eun Ryoung Kim
Clin Exp Pediatr. 2008;51(2):150-155.   Published online February 15, 2008
Purpose : It has been known that breast milk cause prolonged unconjugated hyperbilirubinemia. UGT1A1 is a important gene of uridine diphosphate glucuronosyltransferase (UGT) which has a major role of bilirubin metabolism. These findings suggest that there is a relationship between UGT1A1 gene mutation and prolonged jaundice of breast feeding infant. The aim of study was to investigate whether a polymorphism...
The relation between angiotensin converting enzyme (ACE) gene polymorphism and neonatal hyperbilirubinemia in Korea
Mi Yeoun Kim, Jae Myoung Lee, Ji Sook Kim, Eun Ryoung Kim, Hee Jae Lee, Seo Hyun Yoon, Joo Ho Chung
Clin Exp Pediatr. 2007;50(1):28-32.   Published online January 15, 2007
Purpose : Human angiotensin converting enzyme (ACE) gene shows an insertion/deletion polymorphism in 16 intron, and three genotypes are determined by whether a 287 bp fragment of the DNA is present or not; II, ID and DD genotype. DD genotype has been suggested as a risk factor of chronic nephrotic disease such as IgA nephropathy and diabetic nephropathy, various cardiovascular...
Case Report
A case of congenital neurocutaneous melanosis
Sang Kyun Ha, Jae Myoung Lee, Eun Ryoung Kim, Ho Hwang, Hong Tak Lee
Clin Exp Pediatr. 2006;49(2):212-216.   Published online February 15, 2006
Neurocutaneous melanosis is a rare congenital syndrome characterized by the presence of large or multiple congenital melanocytic nevi and benign pigment cell tumors of the leptomeninges. Neurocutaneous melanosis is thought to represent an error in the morphogenesis of embryonal neuroectoderm. We experienced a neonate who presented with giant, dark colored pigmented nevi covering chest, abdomen, neck and arms, with satellite...